Enterobacteriaceae

Antimicrobial resistance of nosocomial Enterobacteriaceae isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 1670 isolates of Enterobacteriaceae collected in 35 hospitals of 22 cities of …

Multidrug-Resistant Enterobacteriaceae Colonizing Gastrointestinal Tract in Infants with Congenital Heart Disease on Admission to Cardiac Surgery Hospital

We studied 126 children, admitted to cardiac surgery hospital with colonization of the gastrointestinal tract (GIT) by multidrug-resistant Enterobacteriaceae. Criterion for inclusion in the study were children with complex congenital heart disease …

Antimicrobial Resistance of Gram-negative Microorganisms Causing Complicated Intra-abdominal Infections in Russia

Objective. To assess antimicrobial resistance of gram-negative microorganisms causing complicated intra-abdominal infections (IAI) in Russia. Materials and Methods. This was a multicenter (a total of 21 cities), prospective, microbiological study to collect Gram-negative pathogens from patients with complicated IAI. Identification was performed using MALDITOF mass spectrometry. Minimal inhibitory concentrations (MICs) of antibiotics were determined by dilution method according to the current CLSI and EUCAST guidelines. Results. A total of 1908 isolates of gram-negative pathogens was obtained (357 isolates in community-acquired IAI, and 1551 isolates in nosocomial IAI).

In vitro Ceftaroline Activity against Major Bacterial Pathogens n Russia: Results of Multicenter Study

Background. Ceftaroline is a new broad-spectrum cephalosporin with in vitro activity against Gram-positive pathogens, including MRSA, and common Gram-negative pathogens. It is approved for the treatment of acute complicated bacterial skin and skin-structure infections (SSSIs) and community-acquired bacterial pneumonia. Objective. To determine in vitro activity of ceftaroline and other clinically available antimicrobials against major bacterial pathogens from different regions of Russian Federation. Materials and Methods. A total of 2778 consecutive, non-duplicate isolates were collected during multicentre microbiological in vitro study from 36 geographically distinct cities of Russia during 2008–2012.

Antimicrobial Resistance of Nosocomial Enterobacteriaceae Isolates in Russia: Results of National Multicenter Surveillance Study «MARATHON» 2011–2012

Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 573 isolates of Enterobacteriaceae collected in 25 hospitals of 18 cities of …

Characteristics of Enterobacteriaceae Strains Producing CTX-M type ESBL in a Cardiac Surgery Hospital

The study of the prevalence of ESBL CTX-M type of nosocomial strains of Enterobacteriaceae was perfomed. CTX-M enzymes have been identified in all ESBLproducing strains of Enterobacteriaceae. Identified β-lactamases belonged to the four genetic …

Trends in the Prevalence and Susceptibility of ESBL-producing Entererobacteriaceae to Various Antimicrobial Agents in Russian ICUs

The prevalence of extended-spectrum β-lactamase (ESBL) production in nosocomial Enterobacteriaceae isolated in ICUs of various regions of Russia in 1997–1998 and 2003 was studied. We report the dramatic increase in the incidence of ESBLs, attributed …

Trends in the Prevalence and Susceptibility of ESBL-producing Entererobacteriaceae to Various Antimicrobial Agents in Russian ICUs

The prevalence of extended-spectrum β-lactamase (ESBL) production in nosocomial Enterobacteriaceae isolated in ICUs of various regions of Russia in 1997–1998 and 2003 was studied. Here, we report the dramatic increase in the incidence of ESBLs, …

Comparison of Results of Antimicrobial Susceptibility Testing of Gram-negative Aerobic Bacteria by Disc Diffusion on Mueller-Hinton Agar and AGV Medium

Results of the comparative susceptibility testing of Gram-negative aerobic bacteria by disc diffusion method on Mueller-Hinton Agar (MHA) and the AGV medium that are widely used for susceptibility testing in Russia, are presented. The aim of the …

Comparative Activity of Cefepime and Other Antimicrobials Against Nosocomial Gram-Negative Pathogens in Russia

The present in vitro study of antimicrobial susceptibility of nosocomial Gram,negative pathogens to cefepime and other antimicrobials has been performed by the ROSNET study group in 28 medical institutions in Russia. The most active agent against …