Diseases and Pathogens | CMAC

Diseases and Pathogens

Bacterial Vaginosis During Pregnancy: Current State of the Problem and the Role of Antimicrobial Chemotherapy

Pregnancy is an important risk factor for the development of bacterial vaginosis. According to the data of epidemiological studies, the prevalence of this disorder in pregnant women varies from 10% to 40% in different countries. In USA estimated …

Comparative Predictive Value of the Severity Assessment Tools in ICU Patients with Community-Acquired Pneumonia

Validation of the following assessment tools (APACHEII, SOFA, CURB-65, CRB-65, PORT, SMRT-CO) was performed based on data obtained from 300 ICU patients with community-acquired pneumonia (CAP). Predictive value of the scores was determined using …

Antimicrobial Prophylaxis in Colorectal Surgery

Development of the surgical site infections is one the important causes of morbidity and mortality in surgical patients. Surgical site infections significantly prolong the length of hospital stay and increase the cost of hospitalization. Abdominal …

Asthma associated with Chlamydophila pneumoniae-infection

The present open-label, randomized, comparative study of efficacy of 8-week Azithromycin therapy in mildto-moderate stable asthma included 71 patients. After evaluation for C. pneumoniae infection by serologic tests, patients where randomized into 4 …

Legionellosis: the Role in Human Infectious Diseases

In spite of the fact that legionellosis is known as a human infectious disease for more than 25 years there is still quite a few difficulties and open problems. At the present article the following topics are described in detail: taxonomy, general …

Pharmacotherapy of Vulvovaginal Candidiasis According to Pharmacoepidemiology Data and Evidence-Based Medicine

Approximately 75% of women experience at least one episode of acute vulvovaginal candidiasis during their life. In the 1980-90s, almost two-fold increase in fungal vaginitis was observed with increase in number of cases caused by non-albicans strains …

Current Approaches to Diagnosis of Streptococcal Pharyngitis

The antimicrobial agent prescription rate in patients with pharyngitis is excessively high in Russia. Most cases of the disease are caused by viruses, thus administration of antimicrobials is often unjustified. The only common bacterial cause of …

Pneumonia in Nursing Homes: Current View on Problem

Pneumonia is the common bacterial infection among elderly patients in nursing homes and long-term care facilities. Pneumonia in that population is often severe and associated with high mortality. The high prevalence of this infection, diagnostic …

Infectious Complications of the Anti-TNF Therapy: «Praemonitus, Praemunitus»

Tumor necrosis factor (TNF)-blocking agents are one of the new option in the treatment of immune-mediated inflammatory diseases, such as rheumatoid arthritis, Crohn disease, ulcerative colitis. However, anti-TNF therapy is associated with the …

Current state of Anti-Anaerobic Therapy

Over the last years there is an increase in number of publications that address to the failure of empirical therapy of anaerobic infections which is due to the antimicrobial resistance of pathogens. Hence, it is important to have valid local data on …