Clinical Microbiology and Antimicrobial Chemotherapy. 2007; 9(3):244-252
Development of the surgical site infections is one the important causes of morbidity and mortality in surgical patients. Surgical site infections significantly prolong the length of hospital stay and increase the cost of hospitalization. Abdominal surgical operations that involve the incision of the wall of large intestine and rectum are the strict indication for antimicrobial prophylaxis. In this group of patients antimicrobial prophylaxis is significantly reducing the rate of surgical site infections. At the same time there are some reports on the not optimal efficacy of some prophylactic regimens in the patients undergoing abdominal surgery. So, the main aim of this article is to review the evidence based data on antimicrobial prophylaxis in colorectal surgery and to suggest the optimal prophylactic regimens for the real practice.