Diseases and Pathogens

In modern literature, there is insufficient information on the composition of the conjunctival microbiota in children under 1 year of age, and information on its composition in premature infants is virtually absent. Analysis of conjunctival …

Acute liver failure (ALF) is a rapidly developing condition with a broad etiologic factor and incompletely understood mechanisms of pathogenesis. Timely identification of the cause and rapid initiation of etiologic treatment, detection, prevention …

Invasive aspergillosis is a serious disease that can occur in organ transplant recipients. Most often, this complication develops in recipients of lung, heart, and liver transplants. Kidney transplant recipients are less likely to develop the …

Objective. To characterize spectrum of S. pneumoniae serotypes isolated from patients with invasive pneumococcal infection in the Russian Federation. Materials and Methods. The serotype identification of 93 S. pneumoniae isolates obtained from blood and cerebrospinal fluid of patients with various forms of invasive pneumococcal disease was performed using whole-genome sequencing. PCV-13, PCV-15, PCV-20 and PPV-23 coverage of circulated serotypes was estimated using descriptive statistics. Results. The study included 93 S.

Objective. To assess prevalence, etiology, antimicrobial prescribing practices and treatment outcomes of infections in intensive care units in Russia. Materials and Methods. A two-stage (the first stage – October 18, 2022, the second stage – November 18, 2022) multicenter prospective one-day observational study involved 111 intensive care units (ICUs) of 67 centers from 25 cities of the Russian Federation. Each patient was included in the study only once. Data from the medical records of all patients in the ICU on the day of the study were entered by the attending physician into a single electronic individual case report form.

This literature review summarizes actual data on the use of anti-infective drugs in the treatment of brain abscesses, in particular, otorinosnusogenic ones. Mainly the largest publications over the last decade concerning this issue were analyzed. The …

The article analyzes statistical data on the incidence of diphtheria in the Russia at the end of the XX and the beginning of XXI century, provides absolute and relative intensive incidence rates in the country level, examines the patterns of the …

This review provides the characteristics of representatives of the Weissella genus, including W. confusa, W. cibaria, and W. viridescens. The morphological, cultural, biochemical serological properties of these microorganisms belonging to the genus …

Objective. To determine role of ferritin (FT), procalcitonin (PCT) and their ratio (FT/PCT) in the differential diagnosis of viral lung injury and bacterial community-acquired pneumonia (CAP). Materials and Methods. A prospective multicenter study included adult patients with CAP hospitalized in multidisciplinary hospitals from July to November 2023. All patients had their PCT and FT levels determined in addition to the standard examination protocol. Etiological diagnostics included microbiological examination of a respiratory sample and blood (in severe cases), rapid tests for pneumococcal and legionella antigenuria, and molecular testing of respiratory samples to detect DNA/RNA of the most common respiratory viruses and difficult-to-culture or non-cultivate bacterial pathogens.

Antimicrobial therapy is an essential part of treatment of urinary tract infections, often being the only etiological and pathogenetic component of it. At the same time, the rationality of choosing an antimicrobial depends both on the sensitivity of …