Diseases and Pathogens | CMAC

Diseases and Pathogens

Lymphogranuloma Venereum: Epidemic of the Old Disease in New Regions

This paper reviews a current state of the lymphogranuloma venereum in developed countries. Lymphogranuloma venereum is a sexually transmitted disease caused by Chlamydia trachomatis serovars L1, L2, and L3. Over the last years, this infection has …

Incidence of Community-Acquired Pneumonia and Acute Otitis Media in Children 0–5 Years in Russia and Role of S. pneumoniae or H. influenzae in the Etiology of the Diseases

Objective. To estimate the incidence of communityacquired pneumonias and acute otitis media and the role of S. pneumoniae and H. influenzae in these infections in children under 5 years. Materials and Methods. Investigational program PAPIRUS (Prospective Assessment of Pneumococcal Infection in RUSsia), which included multi-center prospective epidemiological study estimating the incidence of community-acquired pneumonia (CAP) and the role of S. pneumoniae and H. influenzae in CAP and acute otitis media (AOM) in children 0-5 years of age in 3 Russian cities (Barnaul, Yekaterinburg and Murmansk) and the prospective multi-center observational cohort study evaluating the incidence of AOM in children under 5 years in the same cities had been performed during 12 months.

Treatment of Acute Tonsillitis/Pharyngitis: Current Guidelines and Russian Local Situation

The article analyzes contemporary recommendations for diagnosis and treatment of acute tonsillopharyngitis, and essential practical aspects for management of patients with this infection considering characteristics of antibiotic resistance profile of …

Persister Microbial Cells: a Novel View on the Old Problem

This review presents a modern view on persister microbial cells, a specific form of latent cells, which is formed in bacterial and fungal populations in stationary phase of growth. Persister cells are found in planktonic populations as well as …

Antibacterial Therapy of Infectious Exacerbations of Chronic Bronchitis: from Pathogen Eradication to Long-Term Relapse-Free Period

Chronic obstructive pulmonary disease (COPD) is a chronic illness that is characterized by recurring exacerbations. Exacerbations lead to the progression of the disease with development of respiratory failure, decreasing of the quality of life of the …

Rhodococcus spp.: Clinical Importance, Diagnosis and Antimicrobial Therapy

The clinical significance of nocardioform bacteria isolated recently in a distinct genus Rhodococcus, as pathogens of infectious diseases in human also has not been sufficiently studied and specified. In the literature there are described a slightly …

Prevention of Hospital-Acquired Pneumonia in Patients with Acute Stroke

Hospital-acquired pneumonia (HAP) is a permanent problem of hospitals, especially intensive care units, where multiple factors such as invasive tests and treatments, aggressive medical therapy, and complex conditions of patient care contribute to …

Short Courses of Antimicrobial Therapy: a New Treatment Paradigm for Community-Acquired Pneumonia?

Over the last years, short treatment courses for different infections, including respiratory tract infections, are increasingly more discussed. This therapeutic approach has some clear benefits: improved compliance, less frequent adverse drug …

The New Approach to the Topical Therapy of Onychomycoses

Onychomycosis is a fungal infection of nails of fingers of the hands or feet, resulting in thinning, and the subsequent destruction, discoloration and desquamation of the nail plate from the nail bed. The etiology of onychomycosis in most cases are …

Review of the 2012 IDSA Guidelines on the Management of Diabetic Foot Infections

Diabetic foot infections (DFIs) are a frequent clinical problem. Properly managed, most of them can be cured, but many patients needlessly undergo amputations because of improper diagnostic and therapeutic approaches. Foot infection should be defined …