Persister Microbial Cells: a Novel View on the Old Problem

Clinical Microbiology and Antimicrobial Chemotherapy. 2013; 15(3):192-197

Type
Journal article

Abstract

This review presents a modern view on persister microbial cells, a specific form of latent cells, which is formed in bacterial and fungal populations in stationary phase of growth. Persister cells are found in planktonic populations as well as bacterial biofilms. Persisters are characterized by tolerance to antimicrobial agents and stress resistance. Persister cells are associated with multiple recurrent medical conditions being refractory to standard treatments. This review also discusses potential measures to reduce or eradicate persister cells population.

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