Clinical Microbiology and Antimicrobial Chemotherapy. 2013; 15(2):86-94
Over the last years, short treatment courses for different infections, including respiratory tract infections, are increasingly more discussed. This therapeutic approach has some clear benefits: improved compliance, less frequent adverse drug reactions, decreased risk of selection and distribution of drug-resistant pathogens, and cost-effectiveness. The main question in discussing short courses of antimicrobial therapy is the following: Is shortened duration of treatment (compared to conventional) associated with decreased treatment efficacy? This paper is intended to find answer to the question with regard to the management of patients with community-acquired pneumonia.