Staphylococcus aureus

Anti-Staphylococcal Effects of Telavancin and Vancomycin in In Vitro Simulations of the Antibiotic Pharmacokinetics

Telavancin (TLV) is an investigational lipoglycopeptide with multiple mechanism of action. It exhibits rapid bactericidal activity against gram-positive bacteria, including methicillin-susceptible and -resistant, glycopeptide-intermediate and …

Epidemiology of Antimicrobial Resistance of S. aureus Isolated from ICU Patients in Russia: Results of Prospective Multicenter Study

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from ICU patients in different regions of Russia. Materials and Methods. A total of 998 clinical strains of S.aureus isolated in 2004–2005 from 998 patients hospitalized in ICU of 32 medical institutions in different parts of Russia. Susceptibility to 16 antimicrobials was determined by agar dilution method in accordance with CLSI recommendations. Results. The prevalence of MRSA among tested strains was 49.

Epidemiology of Antimicrobial Resistance of S. aureus Isolated from ICU Patients in Russia: Results of Prospective Multicenter Study

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from ICU patients in different regions of Russia. Materials and Methods. A total of 998 clinical strains of S.aureus isolated in 2004-2005 from 998 patients hospitalized in ICU of 32 medical institutions in different parts of Russia. Susceptibility to 16 antimicrobials was determined by agar dilution method in accordance with CLSI recommendations. Results. The prevalence of MRSA among tested strains was 49.

Comparative Efficacy of 0.75% Chloramphenicol Ointment and 2% Mupirocin Ointment in the Treatment of Community-Acquired Skin and Soft Tissue Infections

The aim of this study was to assess clinical efficacy of topical chloramphenicol in comparison to topical mupirocin in the treatment of mild to moderate communityacquired skin and soft tissue infections (SSTI). A total of 150 adult immunocompetent …

Comparative Pharmacodynamics of Daptomycin and Vancomycin with Staphylococcus aureus in an in vitro Dynamic Model

To compare the pharmacodynamics of daptomycin (DAP) and vancomycin (VAN) as well as killing kinetics of S. aureus with different MICs were studied at widely ranged AUC/MIC ratios. Two clinical isolates, S. aureus 866 (MICDAP 0.35 µ/ml and MICVAN 0.70 …

Pyoderma in Outpatients

Despite the wide use of antibiotics pyoderma remains one of the important problems of modern medicine. Patients with skin and soft tissue infections, including pyoderma, come to 13 of all patients with infectious diseases in economically …

Community-Acquired MRSA – New Problem of Antimicrobial Resistance

Staphylococcus aureus remains one of the most important human pathogens. Special attention is paid to a new problem – emerging and spreading of methicillin$ resistant strains of S. aureus in the community (CAMRSA). The main differences between …

Epidemiology of Antimicrobial Resistance of Nosocomial Strains of Staphylococcus aureus in Russia: Results of Prospective Multicenter Study

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from hospitalized patients from different regions of Russia. Materials and Methods. A total of 879 clinical strains of S. aureus isolated in 2000–2001 from patients hospitalized in 17medical institutions in different parts of Russia. Susceptibility to 18 antimicrobials: oxacillin, vancomycin, teicoplanin, linezolid, erythromycin, clindamycin, lincomycin, gentamicin, mupirocin, fusidic acid, ciprofloxacin, levofloxacin, moxifloxacin, quinupristin/dalfopristin, rifampicin, trimethoprim/sulfamethoxazole, tetracycline, chloramphenicol was determined by agar dilution method in accordance with the NCCLS recommendations.

Susceptibility of Staphylococcus aureus from Hospitalised Patients to Topical Antimicrobials in Russia

Objective. To determine in vitro activity of fusidic acid and other antimicrobials available for topical use against S. aureus isolated from hospitalised patients. Materials and Methods. A total of 879 clinical strains of S. aureus isolated in 2000-2001 from patients hospitalised in 17 medical institutions in different parts of Russia - 4 in Central region, 2 in North-West region, 3 in South region, 2 in Volga region, 3 in Ural region, 3 in Siberian region, were included in the study.

The Economic Impact of Staphylococcus aureus Infection

Translated and reprinted with permission from «Emerging Infectious Diseases» 1999;5:9-17.

We modeled estimates of the incidence, deaths, and direct medical costs of Staphylococcus aureus infections in hospitalized patients in the New York City …