Identification of a Novel MRSA ST239 Strain Producing Toxic Shock Syndrome Toxin (TSST-1) in a HIV-infected Patient with Pneumonia

Clinical Microbiology and Antimicrobial Chemotherapy. 2011; 13(4):346-353

Journal article


Methicillin-resistant Staphylococcus aureus (MRSA) ST239 is one of the most common nosocomial genotypes worldwide. Typical MRSA ST239 strains do not produce toxic shock syndrome toxin-1 (TSST-1), which is encoded by tst gene at staphylococcal pathogenicity island (SaPI). This study was performed to investigate a novel MRSA ST239 strain producing TSST-1, which is encoded by genes at SaPI2 (designated as SaPI2/R). This strain was isolated from a HIV-infected patient with pneumonia. The results of genotyping by staphylococcal chromosomal cassette showed that the MRSA isolate carried SCCmecIII.1.1.2 type.

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