HIV-infection | CMAC

HIV-infection

Molecular and genetic features of pathogens in patients with unfavorable course of tuberculosis and HIV infection

Objective. To study molecular and genetic features of M. tuberculosis (MTB) and human immunodeficiency virus (HIV) in patients with unfavorable course of HIV infection and tuberculosis. Materials and Methods. A total of 105 patients with HIV infection and newly diagnosed tuberculosis in whom tuberculosis was confirmed by microbiological and molecular genetic methods were included. The follow-up period was at least 6 months. Based on the results of the examination during treatment, all patients were divided into two groups: group 1 – patients with favorable course of HIV infection and tuberculosis (n = 78), group 2 – patients with unfavorable course of HIV infection and tuberculosis (n = 27).

Drug susceptibility of Mycobacterium avium isolated from patients with mycobacteriosis with positive and negative HIV status

Objective. Comparative assessment of in vitro susceptibility of M. avium isolated from patients with mycobacteriosis (MB) with positive and negative HIV status. Materials and Methods. M. avium isolates of were revealed during 2018–2023 from clinical samples of 402 adult patients (≥ 18 years old) in the National Medical Research Center for Phthisiopulmonology and Infectious Diseases of the Ministry of Health of the Russian Federation: 144 strains were isolated from individuals with HIV infection (HIV+) and 258 – from patients with a negative HIV status (HIV-).

Viral Hepatitis E in Patients with Secondary Immunodeficiency

This paper presents a comparative analysis of distribution of hepatitis A, B, C and E as well as opportunistic infections among immunosuppressed patients and healthy people. Results of this epidemiological study suggest hepatitis E as an …

Identification of a Novel MRSA ST239 Strain Producing Toxic Shock Syndrome Toxin (TSST-1) in a HIV-infected Patient with Pneumonia

Methicillin-resistant Staphylococcus aureus (MRSA) ST239 is one of the most common nosocomial genotypes worldwide. Typical MRSA ST239 strains do not produce toxic shock syndrome toxin-1 (TSST-1), which is encoded by tst gene at staphylococcal …

Health Economic Issues of the Treatment of HIV-infection and AIDS

Human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) are one of the most important problems in modern medicine. Authors performed a review of international health economic studies of the HIV/AIDS treatment. …

Antiretroviral drugs

Antiretroviral drugs today are the basis of HIV therapy. The severe and progressive nature of the disease and the need for lifelong therapy make the correct choice of drugs for HIV therapy of particular importance. Alarge number of antiretroviral …