children

Carbapenems are the most appropriate antimicrobials for empiric and pathogen-directed monotherapy in most severe and life-threatening infections in pediatric patients. It can be explained by broadest spectrum of activity, including multidrug …

Invasive mycoses are the substantial cause of morbidity and mortality in immunocompromised children. The prevalence of invasive mycoses in this population is around 25% and the mortality rates are run up to 55-60%. Invasive candidiasis is a major …

Susceptibility testing of 268 clinical strains of H. influenzaе isolated from children in Yekaterinburg during 2000–2005 was performed by disc diffusion method. Resistance to ampicillin was 13%, to II generation cephalosporins – 3%. There was the …

Invasive aspergillosis is a common complication in children with hemoblastosis. This type of mycosis characterized with severe clinical presentations and high attributive mortality. Monotherapy with one of the systemic antimycotics is often using to …

Two groups of children on therapy with monofluoroquinolones were enrolled in this open trial: 169 patients with cystic fibrosis (exacerbation period) and 55 patients with aplastic anemia (neutropenic phase); age was from 6 months to 16 years. The aim …

The prospective study of 19 children (aged of 1 to 17 years) with invasive fungal infections and different forms of immunosupression was conducted. Clinical and microbiological efficacy and safety of caspofungin, as well as analysis of direct costs …

The usage of quinolones and fluoroquinolones (FQ) in children and adolescents as well as in pregnant women is considered in this paper. Based on joint toxicity of FQ observed in immature animals this class of antimicrobial agents is officially …

The educational project “ERA” (Expert Recommendations on Antimicrobial Therapy) was established to join leading experts for the solution of the most important issues in antimicrobial therapy.One of such topics is a proper dosing regimen of …