children

Safety of Monofluoroquinolones in Pediatric Patients

Two groups of children on therapy with monofluoroquinolones were enrolled in this open trial: 169 patients with cystic fibrosis (exacerbation period) and 55 patients with aplastic anemia (neutropenic phase); age was from 6 months to 16 years. The aim …

Efficacy and Safety of Caspofungin in Children with Invasive Fungal Infections

The prospective study of 19 children (aged of 1 to 17 years) with invasive fungal infections and different forms of immunosupression was conducted. Clinical and microbiological efficacy and safety of caspofungin, as well as analysis of direct costs …

Quinolones in Childhood and Pregnancy. Is There a Rationale for Their Use?

The usage of quinolones and fluoroquinolones (FQ) in children and adolescents as well as in pregnant women is considered in this paper. Based on joint toxicity of FQ observed in immature animals this class of antimicrobial agents is officially …

Current Dosing Regimens of Oral Aminopenicillins

The educational project “ERA” (Expert Recommendations on Antimicrobial Therapy) was established to join leading experts for the solution of the most important issues in antimicrobial therapy.One of such topics is a proper dosing regimen of …