Clinical Microbiology and Antimicrobial Chemotherapy. 2013; 15(4):286-294
Analysis of antibiotic usage in children living in orphanages was performed during two time-periods: 2003–2004 and 2009–2010 with the aim to reveal key problems of antibiotic usage in this population, and to develop measures for improvement. It was considered that antibiotic usage in orphanages is often excessive and inappropriate. However, in 2009–2010 some positive trends were noted in comparison with the data from 2003–04: relative decrease in parenteral antibiotic usage, improved compliance with the approved dosing frequency, reduction in frequency of administration of antimicrobials not approved for pediatric use and potentially toxic drugs. Further educational programs are needed to improve physicians’ knowledge of the most common infectious diseases, principles of empiric antibiotic therapy, nonspecific prophylaxis and vaccination to prevent most common infections in children living in orphanages.