children

Objective. To identify specific features of the clinical course of Congo-Crimean hemorrhagic fever (CCHF) in children in order to optimize early and differential diagnosis, management tactics and treatment of pediatric patients Materials and Methods. A retrospective analysis of 159 probable and confirmed cases of Congo-Crimean hemorrhagic fever was carried out in patients admitted to the infectious diseases departments of Shymkent, district hospitals of Turkestan region for the period 2013–2022, of which 39 (24.

Сeftaroline fosamil is a fifth-generation cephalosporin and a unique β-lactam and the only currently registered in the Russian Federation cephalosporin with activity against MRSA. Сeftaroline is approved for use in pediatric practice for the …

This paper presents the first clinical case of combined pulmonary and abdominal M. genavense infection in an otherwise healthy, immunocompetent child with an early treatment response and full recovery. The favorable outcome was determined by rapid …

Objective. To study risk factors, etiology, clinical signs and treatment outcomes of invasive aspergillosis (IA) and mucormycosis combination (IAM) in children. Materials and Methods. A retrospective review of Saint-Petersburg register (1998–2021) of patients with IA was done and children with IAM were included. EORTC/MSGERG 2019 criteria were used for diagnosing and treatment results evaluation of invasive mycosis. We presented a clinical case of IAM in a child with acute lymphoblastic leukemia relapse.

Objective. To assess antimicrobial susceptibility, presence of resistance genes and determine the phenotypic groups of K. pneumoniae, P. aeruginosa and A. baumannii isolated from blood and cerebrospinal fluid of children with nosocomial infections in intensive care units from 2014 to 2020. Materials and Methods. Minimum inhibitory concentrations of antibiotics were determined using the serial broth microdilution method. The identification of genes encoding the production of carbapenemases was carried out using hybridization fluorescence detection.

The increasing number of infections caused by multidrug-resistant gram-negative bacteria in children is a serious problem all over the world. Ceftazidim-avibactam is a promising antimicrobial drug recently approved in Russia for use in pediatric …

Objective. To assess the incidence rate, risk factors and treatment outcomes of mucormycosis in children with hematological malignancies in the large tertiary hematology/oncology center. Materials and Methods. A total of 16 children (9 males/7 females) with mucormycosis were enrolled in a single-center, retrospective study over the period of 2012–2018. All patients had an underlying diagnosis of acute leukemia. Mucormycosis was diagnosed at the different timepoints after chemotherapy (CT) or hematopoietic stem cell transplantation (HSCT) in 15 cases and before CT in 1 case.

Objective. To determine the detection rates of HHV-6A and HHV-6B compared to other herpes viruses in children of different age groups. Materials and Methods. A total of 128 patients with symptoms of respiratory viral infections (RVI) aged from 1 to 16 years and 101 otherwise healthy children. A comprehensive examination of the patients, including ELISA, indirect immunofluorescence assay, rapid culture method, PCR, and determination of nucleotide sequences of HHV-6 was performed.

Objective. To study antibiotic resistance and its association with serotypes of Streptococcus pneumoniae isolated from hospitalized children with community-acquired ENT infections in Belarus during 2013-2016 and to analyze a potential for the use of different antibiotic classes in the treatment of those infections. Materials and Methods. A total of 115 strains isolated from children with acute otitis media and 18 strains isolated from children with acute rhinosinusitis were tested. Antimicrobial susceptibility testing was performed by a broth microdilution method.

Objective. To reveal the prevalence of antimicrobial resistance of H. influenzae, S. pneumoniae, and M. catarrhalis clinical pediatric isolates in Yekaterinburg and Sverdlovsk region during 2013-2015. Materials and Methods. In total 231 H. influenzae, 289 S. pneumoniae, and 266 M. catarrhalis isolates were included in the study. Antimicrobial susceptibility testing was performed partially by disc-diffusion method and partially by automated method, depending on the local practice; β-lacamase production was detected by the nitrocefin disc test.