Clinical Microbiology and Antimicrobial Chemotherapy. 2012; 14(3):176-190
Acute bacterial rhinosinusitis (ABRS) is a common disease in pediatric practice, which takes a fifth place among the causes of antimicrobials administration to children. This paper presents a review of current clinical guidelines on the management of children with ABRS, which have been developed over the last decade. Etiology and spectrum of microorganisms causing ABRS are considered. The paper provides international and Russian data on antimicrobial resistance among the most common pathogens of ABRS – S. pneumoniae and H. influenzae. Clinical diagnosis of ABRS in children as well as the other diagnostic examinations (radiological and microbiological) is described in detail. The main focus is made on antimicrobial therapy of ABRS, particularly a choice of antibiotic (based on severity, risk factors, and regional/ local antimicrobial resistance data) and its dosing regimen. Symptomatic management and adjunctive therapy issues are also considered.