antimicrobials

From 2004 to 2009: Whether Pharmacists’ Recommendations on Acute Urethritis Have Changed over 5 Years?

Clinical Microbiology and Antimicrobial Chemotherapy. 2009; 11(3):253-263
Influence of pharmacists on treatment selection in male patients with acute urethritis in 2003–2004 (Moscow, Smolensk, Kaluga, Kaliningrad) and 2009 (Moscow, Smolensk, Kaluga, Kaliningrad, Tula) was studied. Using “patient simulation” method and …

Etiology of Diabetic Foot Infections and In Vitro Activity of Antimicrobial Agents

Clinical Microbiology and Antimicrobial Chemotherapy. 2009; 11(1):86-89
This article presents the results of the study to determine etiology and antimicrobial susceptibility in diabetic foot infections (DFI). A total of 288 isolates were obtained from patients with confirmed DFI by fine-needle aspiration/biopsy during …

Urinary Tract Infections in Diabetic Patients

Clinical Microbiology and Antimicrobial Chemotherapy. 2008; 10(3):235-244
Urinary tract infections (UTI) in patients with diabetes mellitus are considered complicated UTI. The specific characteristics of UTI in diabetic patients are the following: high prevalence of asymptomatic bacteriuria, involvement of upper urinary …

Analysis of Outpatient Use of Systemic Antimicrobials in Different Regions of Russia

Clinical Microbiology and Antimicrobial Chemotherapy. 2008; 10(1):59-69
The objective of the study was to evaluate the outpatient use of systemic antimicrobials in different regions of Russia. Data on the use of antimicrobials in 24 regions of Russia during year 2004 were collected according to the audit of …

Treatment of Hospitalized Patients with Pneumonia: Levofloxacin vs. Other Treatment Options

Clinical Microbiology and Antimicrobial Chemotherapy. 2007; 9(3):268-278
Translated and reprinted with permission from «Chemotherapie Journal» 2007; 16:41-8.

The main objective of this study was to compare the efficacy of levofloxacin in hospitalized patients suffering from pneumonia to other antibiotic options by …

Current State of Pediatricians Knowledge about Diagnosis, Prophylaxis and Treatment of Dysbacteriosis

Clinical Microbiology and Antimicrobial Chemotherapy. 2006; 8(2):145-150
Russia is the only country, where the term «dysbacteriosis» is used. However, there is no nosologic form such as dysbacteriosis in the ICIDH-10, and effectiveness of the medications used for prophylaxis and treatment of this condition has a lowest …

Problem of Counterfeit Drugs: Focus on Antimicrobials

Clinical Microbiology and Antimicrobial Chemotherapy. 2005; 7(2):167-173
The problem of counterfeit drugs was first discussed at international level in 1985 at the World Health Organization Conference of Experts on the Rational Use of Drugs in Nairobi. Nowadays it is estimated that counterfeit arc up to 10% of allmarketed …

The Use of Antimicrobials in Pregnancy

Clinical Microbiology and Antimicrobial Chemotherapy. 2005; 7(1):77-91
The use of antimicrobials in pregnancy is associated with a potential risk for deleterious effect on fetus and neonate. Pregnancy may be associated with changes in pharmacokinetics because of reduced renal blood flow and glomerular filtration, …

New Approaches to the Optimization of Antimicrobial Therapy of Respiratory Tract Infections Using Pharmacokinetic and Pharmacodynamic Parameters

Clinical Microbiology and Antimicrobial Chemotherapy. 2004; 6(1):22-31
To understand the relationship between drug dose and efficacy, pharmacokinetic (PK) and pharmacodynamic (PD) characteristics need to be integrated. There are two patterns of antimicrobial activity: time-dependent killing and concentration-dependent …

Practice Guidelines on Antimicrobial Therapy of Sinusitis

Clinical Microbiology and Antimicrobial Chemotherapy. 2003; 5(2):167-174
This paper presents data on epidemiology and etiology of sinusitis in Russia as well as antimicrobial susceptibility patterns of most likely pathogens, causing different forms of the disease. Choice of antimicrobials for treatment of different types …