antimicrobials

Medical Problems Associated with Bacterial Biofilms

This paper represents a review of currently available data on microbial communities and biofilms as an important clinical problem. Structure and morphology of microbial biofilm as well as stages and mechanisms of its formation, and genes and factors …

Antimicrobial Susceptibility of Bacterial Strains Contained in the Probiotic Preparation «Linex»

Currently, there is an ever-increasing consumption of probiotics contained in foods, food supplements, and medicinal products. A number of studies to determine efficacy of those products in different medical conditions is also increasing. Meanwhile, …

Pharmacoepidemiologic, Clinical, and Microbiological Study on Antimicrobial Therapy of Inflammatory Diseases of Maxillofacial Area

This paper presents the results of a study to evaluate pharmacological therapy in inflammatory diseases of maxillofacial area in outpatient and hospital settings. The study included a review of medical records for outpatients (n = 600) and …

Infections in Russian ICUs: Results of the Nationwide Multicenter Study

Epidemiological data on the prevalence of infections in ICU is crucial for clinical practice. At the same time in Russia only very limited local information was available. So, the aim of the present study was to evaluate the prevalence and etiology …

Selection of Resistance Associated with the Use of Antimicrobial Agents: Collateral Damage Concept

Collateral damage concept describes an adverse ecological effect associated with the use of antimicrobial agents. The main point is a selection of multidrug-resistant strains and subsequent colonization and infections caused by those microorganisms. …

Analysis of Anti-Infective Therapy in Pregnant Women in Primorskiy Region

Results of retrospective pharmacoepidemiological study in Far East region of Russia within 2004–2008 are presented. 1119 cases of antibacterials administration during the first trimester of pregnancy from 554 medical records were analyzed. Results of …

From 2004 to 2009: Whether Pharmacists’ Recommendations on Acute Urethritis Have Changed over 5 Years?

Influence of pharmacists on treatment selection in male patients with acute urethritis in 2003–2004 (Moscow, Smolensk, Kaluga, Kaliningrad) and 2009 (Moscow, Smolensk, Kaluga, Kaliningrad, Tula) was studied. Using “patient simulation” method and …

Etiology of Diabetic Foot Infections and In Vitro Activity of Antimicrobial Agents

This article presents the results of the study to determine etiology and antimicrobial susceptibility in diabetic foot infections (DFI). A total of 288 isolates were obtained from patients with confirmed DFI by fine-needle aspiration/biopsy during …

Urinary Tract Infections in Diabetic Patients

Urinary tract infections (UTI) in patients with diabetes mellitus are considered complicated UTI. The specific characteristics of UTI in diabetic patients are the following: high prevalence of asymptomatic bacteriuria, involvement of upper urinary …

Analysis of Outpatient Use of Systemic Antimicrobials in Different Regions of Russia

The objective of the study was to evaluate the outpatient use of systemic antimicrobials in different regions of Russia. Data on the use of antimicrobials in 24 regions of Russia during year 2004 were collected according to the audit of …