antimicrobials

Current approaches to prophylaxis and treatment of travelers’ diarrhea

Travelers’ diarrhea is the most common infectious disease in this subpopulation and usually develops within the first week of travel. This review presents summarized data on epidemiology and etiology of travelers’ diarrhea. Nonspecific precautions …

The rating of medical errors in the use of antimicrobials: retrospective clinical pharmacological analysis

Examination of rational pharmacotherapy is one of the major functional duties of the doctor – the clinical pharmacologist. Chemotherapy as etiotropic therapy is one of the most important types of pharmacotherapy. A retrospective analysis of case …

Paediatricians Approach to Prescribing of Systemic Antimicrobials in Outpatient Children with Upper Respiratory Tract and ENT Infections: Data from Multicenter Survey

Objective. Objectives. The study aimed to assess paediatricians knowledge of etiology and approach to systemic antimicrobials (АМ) use in outpatient children with acute respiratory tract infections. Materials and Methods. A questionnaire survey of primary care paediatricians from 17 cities of Russian Federation was performed in 2011–2013 in compliance with the unified methodology. Results. A total of 701 paediatricians (mean age 46,3±10,7, 61,5% with work experience >15 years) took part in the survey.

Safety Issues With the Use of Antimicrobials in Current Clinical Practice

Due to increased use of antibiotics in current clinical practice it is very important to evaluate all risks of antimicrobial therapy. Pharmacovigilance plays a vital role in ensuring that doctors, together with the patient, have enough information …

Medical Problems Associated with Bacterial Biofilms

This paper represents a review of currently available data on microbial communities and biofilms as an important clinical problem. Structure and morphology of microbial biofilm as well as stages and mechanisms of its formation, and genes and factors …

Antimicrobial Susceptibility of Bacterial Strains Contained in the Probiotic Preparation «Linex»

Currently, there is an ever-increasing consumption of probiotics contained in foods, food supplements, and medicinal products. A number of studies to determine efficacy of those products in different medical conditions is also increasing. Meanwhile, …

Pharmacoepidemiologic, Clinical, and Microbiological Study on Antimicrobial Therapy of Inflammatory Diseases of Maxillofacial Area

This paper presents the results of a study to evaluate pharmacological therapy in inflammatory diseases of maxillofacial area in outpatient and hospital settings. The study included a review of medical records for outpatients (n = 600) and …

Infections in Russian ICUs: Results of the Nationwide Multicenter Study

Epidemiological data on the prevalence of infections in ICU is crucial for clinical practice. At the same time in Russia only very limited local information was available. So, the aim of the present study was to evaluate the prevalence and etiology …

Selection of Resistance Associated with the Use of Antimicrobial Agents: Collateral Damage Concept

Collateral damage concept describes an adverse ecological effect associated with the use of antimicrobial agents. The main point is a selection of multidrug-resistant strains and subsequent colonization and infections caused by those microorganisms. …

Analysis of Anti-Infective Therapy in Pregnant Women in Primorskiy Region

Results of retrospective pharmacoepidemiological study in Far East region of Russia within 2004–2008 are presented. 1119 cases of antibacterials administration during the first trimester of pregnancy from 554 medical records were analyzed. Results of …