antimicrobials

Prescribing safe and effective drug therapy is becoming increasingly challenging. Recently, there has been an upward trend in the number of patients experiencing polypragmasy. Thus, according to epidemiological analysis of 180,815 outpatient records …

Objective. To determine the level of basic knowledge of senior students of medical universities in the rational use of AMP. Materials and Methods. Analysis of an anonymous multicenter survey in the framework of the “KANT” project (the full name of the project is “Physicians’ (Students ’) knowledge in antimicrobials usage”), conducted in 2018–2019 in 6 cities of Russia and Kyrgyzstan. Results. The study revealed a low level of knowledge of senior students in the field of antibiotic therapy and the empirical use of AMP.

Antimicrobial resistance is a global challenge for human society. Scientists around the world are trying not to return to the time when antimicrobials were not yet discovered, and millions of people were dying from infections. This article describes …

Objective. To estimate composite indicators of systemic antibiotic consumption in the hospital segment of Saint-Petersburg in 2014–2018. Materials and Methods. Information on the volume and structure of AMP consumption in the hospital segment of St. Petersburg in 2014–2018 was obtained from AlfaRm Databases. The amount of purchased AMP was recalculated in the number of average daily maintenance doses (Defined Daily Dose, DDDs), as well as DDDs per 100 bed-days (DDDh) for each international nonproprietary name of AMP.

Adverse drug reactions affecting gastrointestinal tract, quite often with the development of antibioticassociated diarrhea, are the most common undesirable effects of antibiotic therapy in outpatient practice. This review provides modern approaches …

Patients undergoing cytotoxic chemotherapy and hematopoietic stem-cell transplantation are at risk for infection. The risk of infections increases with the depth and duration of neutropenia, with the greatest risk occurring in patients who experience …

Objective. To select an optimal (in terms of influence on the antibiotic resistance level) and cost-effective structure of antibiotic consumption in a hospital in the management of patients with acute uncomplicated pyelonephritis. Materials and Methods. Based on the literature data as well as a real practice of antibiotic administration, the cost of treatment of an acute uncomplicated pyelonephritis case with different regimens of initial antimicrobial treatment was calculated. Using mathematical modeling, changes in antimicrobial resistance of E.

Travelers’ diarrhea is the most common infectious disease in this subpopulation and usually develops within the first week of travel. This review presents summarized data on epidemiology and etiology of travelers’ diarrhea. Nonspecific precautions …

Examination of rational pharmacotherapy is one of the major functional duties of the doctor – the clinical pharmacologist. Chemotherapy as etiotropic therapy is one of the most important types of pharmacotherapy. A retrospective analysis of case …

Objective. Objectives. The study aimed to assess paediatricians knowledge of etiology and approach to systemic antimicrobials (АМ) use in outpatient children with acute respiratory tract infections. Materials and Methods. A questionnaire survey of primary care paediatricians from 17 cities of Russian Federation was performed in 2011–2013 in compliance with the unified methodology. Results. A total of 701 paediatricians (mean age 46,3±10,7, 61,5% with work experience >15 years) took part in the survey.