antimicrobial therapy

Objective. To study prospectively clinical course of hospital-acquired pneumonia (HAP), mortality, and risk factors for poor outcome as well as etiology and antibiotic resistance of HAP in trauma patients; to assess antimicrobial therapy in patients with head trauma and orthopedic trauma in Smolensk Clinical Hospital of Emergency Medical Care. Materials and Methods. A prospective observational study in 96 patients with head trauma or orthopedic trauma and concurrent HAP, confirmed by clinical examination, chest X-ray, and Clinical Pulmonary Infection Scale (CPIS) score of ≥5.

The most common pathogens of skin and soft tissue infections (SSTI) as well as pharmacodynamics parameters of different antimicrobials against S. aureus are considered in this paper. A total of 80 clinical S. aureus isolates obtained from children (0 …

Objective. To investigate the etiology and antimicrobial resistance patterns of aerobic bacterial pathogens in community- and hospital-acquired intra-abdominal infections (IAI) in the ICUs of two teaching hospitals in one particular city. Materials and Methods. A total of 168 patients with peritonitis (122 community-acquired, 46 nosocomial) were included in the study. Susceptibility testing was performed by agar dilution method according to CLSI recommendations. Results. Clinically significant aerobic pathogens were isolated in 61.

This review contains brief information on the epidemiology of salmonellosis as well as the modern classification and nomenclature of Salmonella genus. The main mechanisms of antimicrobial resistance in Salmonella and their prevalence are summarized. …

Piperacillin/tazobactam, penicillin/beta-lactamase inhibitor combination, has a broad antimicrobial spectrum, including most gram-positive cocci and gram-negativeaerobic and anaerobic bacteria (including beta-lactamase producing microorganisms). …

Efficacy of antimicrobial treatment regimens in pregnant or non-pregnant women with bacterial vaginosis (BV) is difficult to evaluate. It’s due to variability of the diagnosis and cure criteria currently used in clinical studies. This paper …

Choice of empiric therapy should be based on complex of data on etiology and local antimicrobial resistance trends as well as on clinical-economic analysis. According to our results, from the pharmacoeconomic point of view the most optimal agents for …

The objectives of this study were to investigate etiology of acute bacterial rhinosinusitis (ABR) in young soldiers, to determine susceptibility to different antimicrobial agents and to assess clinical efficacy of antimicrobial therapy in ABR. …

Community-acquired pneumonia (CAP) is the 4-8th leading killer of people worldwide and the most leading cause of death from infections in US. This article is a review of innovations and differences between the recent American Thoracic Society (ATS) …

Fournier’s gangrene is a relatively rare disease and comprises specific form of necrotizing fasciitis. This review presents a history of this disease. Several controversial issues, such as etiology, which is polymicrobial and to some extent depends …