antimicrobial therapy

Optimizing the Management of Community-Acquired Pneumonia in Hospitalized Patients on the Basis of Modifiable Factors

Choice of empiric therapy should be based on complex of data on etiology and local antimicrobial resistance trends as well as on clinical-economic analysis. According to our results, from the pharmacoeconomic point of view the most optimal agents for …

Acute Bacterial Rhinosinusitis in Young Soldiers: Etiology, Susceptibility and Antimicrobial Therapy

The objectives of this study were to investigate etiology of acute bacterial rhinosinusitis (ABR) in young soldiers, to determine susceptibility to different antimicrobial agents and to assess clinical efficacy of antimicrobial therapy in ABR. …

Current Guidelines for the Management of Adults with Community-Acquired Pneumonia: Way to a Single Standard

Community-acquired pneumonia (CAP) is the 4-8th leading killer of people worldwide and the most leading cause of death from infections in US. This article is a review of innovations and differences between the recent American Thoracic Society (ATS) …

Fournier’s Gangrene

Fournier’s gangrene is a relatively rare disease and comprises specific form of necrotizing fasciitis. This review presents a history of this disease. Several controversial issues, such as etiology, which is polymicrobial and to some extent depends …

Patient Compliance with Antimicrobial Therapy of Lower Respiratory Tract Infections

Methods to improve patient compliance with treatment are rarely used by physicians in their practice. It may be in part because of the lack of adequate information on this issue. This paper reviews adherence of the patients with respiratory tract …

Efficacy and Safety of Josamycin in the Treatment of Mild-to-Moderate Community-Acquired Pneumonia: Results of Multicenter Clinical Study

Multicenter prospective non-comparative open-label clinical study to assess clinical and microbiological efficacy and safety of josamycin (16-memebered macrolide) in adults with non-severe community-acquired pneumonia (CAP) was performed. Patients …

Pneumonia in Nursing Homes: Current View on Problem

Pneumonia is the common bacterial infection among elderly patients in nursing homes and long-term care facilities. Pneumonia in that population is often severe and associated with high mortality. The high prevalence of this infection, diagnostic …

Assessment of Mortality Rate and Efficacy of Antimicrobial Therapy in Patients with Community-Acquired Pneumonia in Sverdlovsk Region

Efficacy of regional standard of care «CommunityAcquired Pneumonia» and Sverdlovsk regional healthcare program «Intensive Care» were assessed. This paper presents results of retrospective analysis of ICU hospitalizations for severe community-acquired …

Review of the IDSA Practice Guidelines for the Management of Bacterial Meningitis

In this paper currently available data on the management, diagnosis and treatment of bacterial meningitis were discussed in accordance with the principles evidencebased medicine. The guideline represents data published through May 2004 in this …

Lower Respiratory Tract Infections in Adult Patients: Diagnosis, Antimicrobial Therapy and Prophylaxis (According to the Guidelines of European Respiratory Society and European Society of Clinical Microbiology and Infectious Diseases)

According to the Guidelines of European Respiratory Society and European Society of Clinical Microbiology and Infectious Diseases.

Clinical guidelines that comply with the principles of evidence-based medicine are one of the most trustworthy sources …