Antimicrobial Resistance and Therapy of Salmonella Infections

Clinical Microbiology and Antimicrobial Chemotherapy. 2009; 11(4):305-326

Journal article


This review contains brief information on the epidemiology of salmonellosis as well as the modern classification and nomenclature of Salmonella genus. The main mechanisms of antimicrobial resistance in Salmonella and their prevalence are summarized. Data on antimicrobial resistance for the most common S. enterica erotypes are described in detail. International recommendations on susceptibility testing in routine practice are presented. The indications for antibiotic therapy and the ways of optimizing a choice of antimicrobials for the treatment of infections caused by nontyphoid Salmonella serotypes and typhoid/paratyphoid fever are provided. A focus on current antimicrobial treatment regimens for patients with Salmonella infections based on experimental and clinical data is made in this paper.

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