antimicrobial therapy | CMAC

antimicrobial therapy

Antimicrobial Resistance of S. aureus Isolated from Infants with Skin and Soft Tissue Infections

The most common pathogens of skin and soft tissue infections (SSTI) as well as pharmacodynamics parameters of different antimicrobials against S. aureus are considered in this paper. A total of 80 clinical S. aureus isolates obtained from children (0 …

Etiology and Antimicrobial Resistance of Hospital-acquired and Community-acquired Intra-Abdominal Infections in ICUs of Two Teaching Hospitals

Objective. To investigate the etiology and antimicrobial resistance patterns of aerobic bacterial pathogens in community- and hospital-acquired intra-abdominal infections (IAI) in the ICUs of two teaching hospitals in one particular city. Materials and Methods. A total of 168 patients with peritonitis (122 community-acquired, 46 nosocomial) were included in the study. Susceptibility testing was performed by agar dilution method according to CLSI recommendations. Results. Clinically significant aerobic pathogens were isolated in 61.

Antimicrobial Resistance and Therapy of Salmonella Infections

This review contains brief information on the epidemiology of salmonellosis as well as the modern classification and nomenclature of Salmonella genus. The main mechanisms of antimicrobial resistance in Salmonella and their prevalence are summarized. …

Microbiological and Clinical Issues on the Use of Piperacillin/Tazobactam in the Treatment of Severe Infections

Piperacillin/tazobactam, penicillin/beta-lactamase inhibitor combination, has a broad antimicrobial spectrum, including most gram-positive cocci and gram-negativeaerobic and anaerobic bacteria (including beta-lactamase producing microorganisms). …

Current Approaches to Antimicrobial Therapy of Bacterial Vaginosis

Efficacy of antimicrobial treatment regimens in pregnant or non-pregnant women with bacterial vaginosis (BV) is difficult to evaluate. It’s due to variability of the diagnosis and cure criteria currently used in clinical studies. This paper …

Optimizing the Management of Community-Acquired Pneumonia in Hospitalized Patients on the Basis of Modifiable Factors

Choice of empiric therapy should be based on complex of data on etiology and local antimicrobial resistance trends as well as on clinical-economic analysis. According to our results, from the pharmacoeconomic point of view the most optimal agents for …

Acute Bacterial Rhinosinusitis in Young Soldiers: Etiology, Susceptibility and Antimicrobial Therapy

The objectives of this study were to investigate etiology of acute bacterial rhinosinusitis (ABR) in young soldiers, to determine susceptibility to different antimicrobial agents and to assess clinical efficacy of antimicrobial therapy in ABR. …

Current Guidelines for the Management of Adults with Community-Acquired Pneumonia: Way to a Single Standard

Community-acquired pneumonia (CAP) is the 4-8th leading killer of people worldwide and the most leading cause of death from infections in US. This article is a review of innovations and differences between the recent American Thoracic Society (ATS) …

Fournier’s Gangrene

Fournier’s gangrene is a relatively rare disease and comprises specific form of necrotizing fasciitis. This review presents a history of this disease. Several controversial issues, such as etiology, which is polymicrobial and to some extent depends …

Patient Compliance with Antimicrobial Therapy of Lower Respiratory Tract Infections

Methods to improve patient compliance with treatment are rarely used by physicians in their practice. It may be in part because of the lack of adequate information on this issue. This paper reviews adherence of the patients with respiratory tract …