antimicrobial resistance

Resultst of the Multicentre study of Nasopharyngeal Isolates of Haemophilus influenzae from Healthy Children in Day-Care Centers

Clinical Microbiology and Antimicrobial Chemotherapy. 2002; 4(1):33-41

The rates of nasopharyngeal carriage of Haemophilus influenzae and epidemiology of its antimicrobial resistance in healthy children from day-care centers have been investigated. The overall rate of nasopharyngeal H.influenzae carriage was 44%. The …

Specificities of The Susceptibility Testing by Disk-Diffusion Method

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(4):348-354

The approach to administration of antimicrobials is often based on the results of microbiological studies that include microorganism isolation, identification and, most important, susceptibility testing. Majority of microbiological laboratories in …

Role of Fusidic Acid in Clinical Practice

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(4):324-338

The widespread of multy-resistant Gram-positive pathogens, especially methicillin-resistant staphylococci made us to reconsider our attitude to such an «old» drug as fusidic acid and to draw attention to its usefulness in therapy of the …

β-Lactamases of Aerobic Gram-Negative Bacteria: Description, Principles of Classification, Methods of Detection and Typing

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(3):223-242

β-Lactamases are represented by extensive range of genetically and functionally different enzymes that are able to destroy β-lactams that leads to development of resistance to these antibiotics in β-lactamases producing bacteria. Intrinsic production …

Detection of Extended Spectrum β-lactamases by Phenotypic Methods in Gram-negative Bacteria

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(2):183-189

Production of extended-spectrum β-lactamases (ESBL) is the one of most widespread and clinically significant mechanism of resistance to modern β-lactams in members of the family Enterobacteriaceae. But the effectiveness of routine methods of …

Mechanisms of Resistance to Aminoglycosides in Gram-negative Nosocomial Bacteria in Russia: Results of Multicenter Study

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(2):111-125

The mechanisms of resistance to aminoglycoside antibiotics in Gram-negative nosocomial pathogens isolated in four Russian hospitals were studied. The most common and almost exclusive mechanism of aminoglycoside resistance was production of …

Enterococcal Carriage and Antimicrobial Resistance in Premature Born Unit

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(1):28-38

Sensitivity of 100 enterococcal strains isolated from faeces in premature born unit to 15 antimicrobial agents has been studied. 33 strains of Enterococcus faecalis, 61 strains of Enterococcus faecium, 4 strains of Enterococcus casseliflavus and 2 …