Specificities of The Susceptibility Testing by Disk-Diffusion Method

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(4):348-354

Journal article


The approach to administration of antimicrobials is often based on the results of microbiological studies that include microorganism isolation, identification and, most important, susceptibility testing. Majority of microbiological laboratories in Russia for the susceptibility testing use disk-diffusion method. This method is technically simple and has good reproducibility. But at the same time there are some specific features that may lead to incorrect results. In present article the main specificities of disk-diffusion method as well as common sources of incorrect results are indicated, practical recommendations for the improvement of quality of susceptibility testing by disk-diffusion method are given.

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