Clinical Microbiology and Antimicrobial Chemotherapy. 2002; 4(1):70-82
Acute rhinosinusitis is one of the most common disorders in otolaryngology and is on 5th place among all diseases based on the amount of all prescribed antimicrobials. But a number of problems in the antimicrobial therapy of this pathology still remain, among which the overuse of antibiotics and administration of antibiotics without taking into account the activity against the most common pathogens are the main. The review of four recent recommendations on diagnostic and therapy of acute rhinosinusitis is given in this article. The attention is focused on the differential diagnostic of viral and bacterial rhinosinusitis, and the significance of different methods of diagnostic procedures. The current data on the antimicrobial resistance trends in common bacterial pathogens are given. Principles of choice of antimicrobials and therapeutic regimens are described. Validity of administration of non-antimicrobial therapy is analyzed on the basis of evidence-based data.