H. influenzae

Objective. To reveal the prevalence of antimicrobial resistance of H. influenzae, S. pneumoniae, and M. catarrhalis clinical pediatric isolates in Yekaterinburg and Sverdlovsk region during 2013-2015. Materials and Methods. In total 231 H. influenzae, 289 S. pneumoniae, and 266 M. catarrhalis isolates were included in the study. Antimicrobial susceptibility testing was performed partially by disc-diffusion method and partially by automated method, depending on the local practice; β-lacamase production was detected by the nitrocefin disc test.

Objective. To estimate the incidence of communityacquired pneumonias and acute otitis media and the role of S. pneumoniae and H. influenzae in these infections in children under 5 years. Materials and Methods. Investigational program PAPIRUS (Prospective Assessment of Pneumococcal Infection in RUSsia), which included multi-center prospective epidemiological study estimating the incidence of community-acquired pneumonia (CAP) and the role of S. pneumoniae and H. influenzae in CAP and acute otitis media (AOM) in children 0-5 years of age in 3 Russian cities (Barnaul, Yekaterinburg and Murmansk) and the prospective multi-center observational cohort study evaluating the incidence of AOM in children under 5 years in the same cities had been performed during 12 months.

Susceptibility testing of 268 clinical strains of H. influenzaе isolated from children in Yekaterinburg during 2000–2005 was performed by disc diffusion method. Resistance to ampicillin was 13%, to II generation cephalosporins – 3%. There was the …

Materials and Methods. The aim of the study was to determine the structure of bacterial pathogens and their antimicrobial resistance in adult patients with acute maxillary sinusitis. A total of 311 strains isolated from 442 adult patients with acute maxillary sinusitis were included in the study during 2000–2003. Results. Clinically significant bacterial pathogens were isolated in 65.4% of patients; among them single microorganism were found in 87.3% of cases, >2 – in 12.

Acute rhinosinusitis is one of the most common disorders in otolaryngology and is on 5th place among all diseases based on the amount of all prescribed antimicrobials. But a number of problems in the antimicrobial therapy of this pathology still …