antimicrobial resistance

At present, β-lactams are the most commonly used antimicrobials, but their clinical efficacy may be reduced because of the spread of antimicrobial resistance. The most important mechanism of resistance to β-lactams is an inhibition by the microbial …

A variety of resistance mechanisms and free transfer of resistance genes whithin a gender as well as among Enterobacteriaceae lead to a number of problems in the choice of antibacterial therapy of shigellosis. Many conventional antimicrobials used …

Materials and Methods. The aim of the study was to determine the structure of bacterial pathogens and their antimicrobial resistance in adult patients with acute maxillary sinusitis. A total of 311 strains isolated from 442 adult patients with acute maxillary sinusitis were included in the study during 2000–2003. Results. Clinically significant bacterial pathogens were isolated in 65.4% of patients; among them single microorganism were found in 87.3% of cases, >2 – in 12.

Nonfermenting gram-negative rods (NGR) are one of the leading nosocomial pathogens. Among them Pseudomonas aeruginosa, Acinetobacter baumannii, Pseudomonas aeruginosa, Acinetobacter spp., Burkholderia spp., Stenotrophomonas spp., and Chryseobacterium …

To study the microbial and susceptibility patterns in COPD patients with acute respiratory failure (ARF) we performed a prospective cohort study in patients with ARF admitted to our acute care hospital. Quantitative cultures of expectorated sputum or …

In the treatment of uncomplicated urinary tract infec-tions the following groups of antimicrobial are of clinical use: fluoroquinolones, trimethoprim/sulfamethoxazole, nitrofurantoin, fosfomycin (one dose). In uncomplicated acute cystitis the short …

The present analyzed study the level, structure and phenotypes of antimicrobial resistance of Streptococcus pyogenes in different regions of Russia and to evaluate their dynamics in period from 1999 to 2003. A total of 103 S. pyogenes from 8 cities …

In developed countries as well as in Russia enteric fever occurs rarely, whereas several areas in the world are still endemic. At present, prevalence of resistance to most of conventional antimicrobials in Salmonella enterica serotype Typhi is …

Staphylococcus aureus remains one of the most important human pathogens. Special attention is paid to a new problem – emerging and spreading of methicillin$ resistant strains of S. aureus in the community (CAMRSA). The main differences between …

The recent approaches to the treatment of endocarditis caused by Enterococcus spp., including strains that are resistant to conventional therapy, are discussed in the article. The possible ways of reduction of nephrotoxicity in elder patients and in …