Resistance in Shigella spp. and Modern Approaches to Antimicrobial Therapy of Shigellosis

Clinical Microbiology and Antimicrobial Chemotherapy. 2005; 7(4):350-368

​ Maleev V.V., Ivanov A.S., Stratchounski L.S.
shigellosis Shigella spp antimicrobial resistance antimicrobial therapy
Section
Antimicrobial Resistance
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2005; 7(4):350-368

Abstract

A variety of resistance mechanisms and free transfer of resistance genes whithin a gender as well as among Enterobacteriaceae lead to a number of problems in the choice of antibacterial therapy of shigellosis. Many conventional antimicrobials used for treatment of shigellosis such as ampicillin, co-trimoxazole and tetracyclynes lost their activity. The role of the different classes of antimicrobials in the treatment of shigellosis is discussed in this review.

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