Обзор международных согласительных рекомендаций по оптимальному использованию полимиксинов | КМАХ

Обзор международных согласительных рекомендаций по оптимальному использованию полимиксинов

Клиническая микробиология и антимикробная химиотерапия. 2019; 21(4):282-309

​ Елисеева Е.В., Азизов И.С., Зубарева Н.А.
10.36488/cmac.2019.4.282-309
полимиксины колистин полимиксин В рекомендации
Раздел
Антимикробные препараты
Тип
Обзор
Публикация
Клиническая микробиология и антимикробная химиотерапия. 2019; 21(4):282-309

Аннотация

Полимиксины часто являются одними из немногих, а иногда единственными, антимикробными препаратами, сохраняющими in vitro активность в отношении проблемных резистентных возбудителей. Однако их применение связано с целым рядом дискуссионных вопросов, включая определение чувствительности, фармакокинетические и фармакодинамические параметры, оптимальные режимы дозирования, возможности комбинированной терапии. Ответы на эти вопросы максимально подробно изложены в международных согласительных рекомендациях по оптимальному использованию полимиксинов, разработанных следующими научными сообществами: Американской коллегией клинической фармации (ACCP), Европейским обществом по клинической микробиологии и инфекционным болезням (ESCMID), Американским обществом по инфекционным болезням (IDSA), Международным обществом антиинфекционной фармакологии (ISAP), Обществом медицины критических состояний (SCCM) и Обществом фармацевтов по инфекционным заболеваниям (SIDP).

Елисеева Екатерина Валерьевна

ФГБОУ ВО «Тихоокеанский государственный медицинский университет» Минздрава России, Владивосток, Россия

Азизов Илья Сулейманович

НИИ антимикробной химиотерапии ФГБОУ ВО СГМУ Минздрава России, Смоленск, Россия

Зубарева Н.А.

ФГБОУ ВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России, Пермь, Россия

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