urinary tract infections

Experience with the use of an automated system for diagnosis of urinar y tract infections

Objective. To compare results of microbiological examination obtained on rapid automated system with semiquantitative plate culture to assess possibility and necessity of using the system in urine examination. Materials and Methods. The study included 231 urine samples collected from February to July 2023 from patients at Lomonosov Moscow State University Medical Research and Educational Center. The samples were cultured according to the standards of urine microbiological examination using chromogenic media and using an automatic HB&L system (Alifax, Italy) for 4 h.

War and Peace: the difficult treatment of urinary tract infections and fosfomycin trometamol

The title of this review “War and peace” is not accidental and the analogies with a well-known literary masterpiece have absolutely justified ground. As in the case of Lev Tolstoy’s novel this title has a profound philosophical meaning, although at …

Oral third-generation cephalosporins in the treatment of community-acquired urinary tract infections

Cephalosporins are one of the most commonly used antimicrobials for the treatment of variety of bacterial infections. Prudent use of the third-generation cephalosporins is important for the control of spread of cephalosporin-resistant Gram-negative …

Cefotaxime/sulbactam: clinical and pharmacological characteristics

The recently approved cefotaxime/sulbactam, combination of third-generation cephalosporin (cefotaxime) and beta-lactamase inhibitor (sulbactam), can combat resistance mechanisms associated with the production of serine beta-lactamases, including some …

Ceftolozane/tazobactam – the «new player» in a battle against multiresistant pathogens

Ceftolozane/tazobactam is a new combined antibacterial agent for the treatment of infections caused by gram-negative microorganisms, P. aeruginosa in particular, including strains resistant to other clinically available antimicrobials. In this paper …

Oral Third-Generation Cephalosporins in Current Outpatient Clinical Practice

This paper presents current issues with the oral thirdgeneration cephalosporins in outpatient clinical practice. These data are based on the principles of appropriate antimicrobial therapy, national antimicrobial susceptibility data, and …

«Respiratory» Fluoroquinolones – the Neoclassics of Antimicrobial Chemotherapy

«Respiratory» fluoroquinolones, unlike previous generations, have higher activity against Gram-positive pathogens causing important infections in humans. Broad antimicrobial spectrum, ability to overwhelm some bacterial resistance mechanisms, absence …

Current State of Antibiotic Resistance of Pathogens Causing Community-Acquired Urinary Tract Infections in Russia: «DARMIS» Study (2010–2011)

Objective. Objectives. To investigate etiology and susceptibility of pathogens causing community-acquired urinary tract infections (UTIs) in different regions of Russia in various patients’ subsets to the most clinically used antimicrobials. Materials and Methods. A total of 903 uropathogens isolated from urine samples of children and adults of all age groups with acute (and recurrence of chronic) community-acquired UTIs, including pregnant women with asymptomatic bacteriuria were collected in 26 centers of 18 cities in Russia during 2010–2011 and included in the «DARMIS» study.

Current Aspects of Antibiotic Choice in the Treatment of Acute Uncomplicated Cystitis

Acute uncomplicated cystitis is one of the most prevalent community-acquired infections in urological practice. One of the crucial moments in the therapy of urinary tract infections is the administration of antibacterial drugs. The following groups …

Urinary Tract Infections in Adolescent Females in Case of Isolation of STDs Causative Agents

Among adolescent children urinary tract infections (UTI) occurs in around 1% of male and up to 3% of female persons. In adolescent girls during the last decades the frequency of sexually transmitted infections (STI) is rising. Non-treated infections …