Staphylococcus aureus | CMAC

Staphylococcus aureus

Antimicrobial Resistance of Microorganisms Causing Chronic Post-Traumatic Osteomyelitis

This paper presents the results of a microbiological study of clinical specimens obtained from 64 patients with chronic post-traumatic osteomyelitis of long bones during the 2011–2013. A total of 136 clinical strains were isolated and identified to a …

Antimicrobial Resistance of Nosocomial Staphylococcus aureus Isolates in Russia: Results of National Multicenter Surveillance Study «MARATHON» 2011–2012

In total 284 clinical nosocomial S. aureus strains isolated in 2011–2012 from patients hospitalized in 25 hospitals in 18 Russian cities were included in the study. Susceptibility to 19 antimicrobials was assessed by serial dilution method in …

Genotyping of Staphylococcus aureus Isolates in Outbreak of Exfoliative Dermatitis in Neonates

Staphylococcus aureus is known as the leading pathogen in hospital-acquired infections and the most common cause of skin and soft tissues. The present study aimed to test the genetic background of MSSA isolates obtained from pediatric patients and …

A New Method for Evaluation of Antimicrobial Resistance of Bacteria in Biofilms

At the present article we evaluate a relatively new method of the evaluation of activity of antimicrobials against bacterial biofilms. This method combines the possibilities of simultaneous evaluation of bacterial survival in biofilm in the presence …

Identification of a Novel MRSA ST239 Strain Producing Toxic Shock Syndrome Toxin (TSST-1) in a HIV-infected Patient with Pneumonia

Methicillin-resistant Staphylococcus aureus (MRSA) ST239 is one of the most common nosocomial genotypes worldwide. Typical MRSA ST239 strains do not produce toxic shock syndrome toxin-1 (TSST-1), which is encoded by tst gene at staphylococcal …

Detection of Hungarian Pandemic MRSA Clone in Russia

Since 1961, pandemic methicillin-resistant S. aureus (MRSA) clones causing severe nosocomial infections have been distributed worldwide. The Hungarian clone having ST239 genotype and Staphylococcal cassette chromosome mec (SCCmec) type III is one of …

Prediction of Development of Antimicrobial Resistance in In-vitro Dynamic Models of Different Dosage Regiments

According to the mutant selection window (MSW) hypothesis resistant mutants are selected at antibiotic concentrations above the MIC but below the mutant prevention concentration (MPC). There are contradictory reports on the relationships between MIC- …

Anti-Staphylococcal Effects of Telavancin and Vancomycin in In Vitro Simulations of the Antibiotic Pharmacokinetics

Telavancin (TLV) is an investigational lipoglycopeptide with multiple mechanism of action. It exhibits rapid bactericidal activity against gram-positive bacteria, including methicillin-susceptible and -resistant, glycopeptide-intermediate and …

Epidemiology of Antimicrobial Resistance of S. aureus Isolated from ICU Patients in Russia: Results of Prospective Multicenter Study

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from ICU patients in different regions of Russia. Materials and Methods. A total of 998 clinical strains of S.aureus isolated in 2004–2005 from 998 patients hospitalized in ICU of 32 medical institutions in different parts of Russia. Susceptibility to 16 antimicrobials was determined by agar dilution method in accordance with CLSI recommendations. Results. The prevalence of MRSA among tested strains was 49.

Epidemiology of Antimicrobial Resistance of S. aureus Isolated from ICU Patients in Russia: Results of Prospective Multicenter Study

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from ICU patients in different regions of Russia. Materials and Methods. A total of 998 clinical strains of S.aureus isolated in 2004-2005 from 998 patients hospitalized in ICU of 32 medical institutions in different parts of Russia. Susceptibility to 16 antimicrobials was determined by agar dilution method in accordance with CLSI recommendations. Results. The prevalence of MRSA among tested strains was 49.