Staphylococcus aureus

A New Method for Evaluation of Antimicrobial Resistance of Bacteria in Biofilms

Clinical Microbiology and Antimicrobial Chemotherapy. 2012; 14(4):303-308

At the present article we evaluate a relatively new method of the evaluation of activity of antimicrobials against bacterial biofilms. This method combines the possibilities of simultaneous evaluation of bacterial survival in biofilm in the presence …

Identification of a Novel MRSA ST239 Strain Producing Toxic Shock Syndrome Toxin (TSST-1) in a HIV-infected Patient with Pneumonia

Clinical Microbiology and Antimicrobial Chemotherapy. 2011; 13(4):346-353

Methicillin-resistant Staphylococcus aureus (MRSA) ST239 is one of the most common nosocomial genotypes worldwide. Typical MRSA ST239 strains do not produce toxic shock syndrome toxin-1 (TSST-1), which is encoded by tst gene at staphylococcal …

Detection of Hungarian Pandemic MRSA Clone in Russia

Clinical Microbiology and Antimicrobial Chemotherapy. 2011; 13(2):188-195

Since 1961, pandemic methicillin-resistant S. aureus (MRSA) clones causing severe nosocomial infections have been distributed worldwide. The Hungarian clone having ST239 genotype and Staphylococcal cassette chromosome mec (SCCmec) type III is one of …

Prediction of Development of Antimicrobial Resistance in In-vitro Dynamic Models of Different Dosage Regiments

Clinical Microbiology and Antimicrobial Chemotherapy. 2009; 11(2):152-160

According to the mutant selection window (MSW) hypothesis resistant mutants are selected at antibiotic concentrations above the MIC but below the mutant prevention concentration (MPC). There are contradictory reports on the relationships between MIC- …

Anti-Staphylococcal Effects of Telavancin and Vancomycin in In Vitro Simulations of the Antibiotic Pharmacokinetics

Clinical Microbiology and Antimicrobial Chemotherapy. 2009; 11(1):56-65

Telavancin (TLV) is an investigational lipoglycopeptide with multiple mechanism of action. It exhibits rapid bactericidal activity against gram-positive bacteria, including methicillin-susceptible and -resistant, glycopeptide-intermediate and …

Epidemiology of Antimicrobial Resistance of S. aureus Isolated from ICU Patients in Russia: Results of Prospective Multicenter Study

Clinical Microbiology and Antimicrobial Chemotherapy. 2008; 10(4):333-344

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from ICU patients in different regions of Russia. Materials and Methods. A total of 998 clinical strains of S.aureus isolated in 2004–2005 from 998 patients hospitalized in ICU of 32 medical institutions in different parts of Russia. Susceptibility to 16 antimicrobials was determined by agar dilution method in accordance with CLSI recommendations. Results. The prevalence of MRSA among tested strains was 49.

Epidemiology of Antimicrobial Resistance of S. aureus Isolated from ICU Patients in Russia: Results of Prospective Multicenter Study

Клиническая Микробиология и Антимикробная Химиотерапия. 2008; 10(3):290-301

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from ICU patients in different regions of Russia. Materials and Methods. A total of 998 clinical strains of S.aureus isolated in 2004-2005 from 998 patients hospitalized in ICU of 32 medical institutions in different parts of Russia. Susceptibility to 16 antimicrobials was determined by agar dilution method in accordance with CLSI recommendations. Results. The prevalence of MRSA among tested strains was 49.

Comparative Efficacy of 0.75% Chloramphenicol Ointment and 2% Mupirocin Ointment in the Treatment of Community-Acquired Skin and Soft Tissue Infections

Clinical Microbiology and Antimicrobial Chemotherapy. 2007; 9(1):57-65

The aim of this study was to assess clinical efficacy of topical chloramphenicol in comparison to topical mupirocin in the treatment of mild to moderate communityacquired skin and soft tissue infections (SSTI). A total of 150 adult immunocompetent …

Comparative Pharmacodynamics of Daptomycin and Vancomycin with Staphylococcus aureus in an in vitro Dynamic Model

Clinical Microbiology and Antimicrobial Chemotherapy. 2006; 8(2):186-192

To compare the pharmacodynamics of daptomycin (DAP) and vancomycin (VAN) as well as killing kinetics of S. aureus with different MICs were studied at widely ranged AUC/MIC ratios. Two clinical isolates, S. aureus 866 (MICDAP 0.35 µ/ml and MICVAN 0.70 …

Pyoderma in Outpatients

Clinical Microbiology and Antimicrobial Chemotherapy. 2005; 7(3):255-270

Despite the wide use of antibiotics pyoderma remains one of the important problems of modern medicine. Patients with skin and soft tissue infections, including pyoderma, come to ¹⁄₃ of all patients with infectious diseases in economically …