candidemia

In house method for rapid identification of fungi from fungus-positive bottles by MALDI-TOF mass spectrometry in patients with bloodstream infection

Objective. To present the results of using in-house method for rapid identification of fungi from funguspositive bottles with routine conventional culture-based identification by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in patients with bloodstream infection. Materials and Methods. Prospective study was performed from 2016 to 2019 at the National Research Center for Hematology, Moscow. During the study period, all blood cultures (BC) bottles obtained from hematological patients were incubated in the BACTEC FX system (Becton Dickinson, USA).

Biofilm formation by Candida spp. isolated from blood culture in patients with or without hematological malignancies

Objective. To evaluate the biofilm formation by isolates of Candida spp. obtained from blood culture in patients with or without hematological malignancies. Materials and Methods. Biofilm formation by Candida spp. was determined by the method of Pierce C. and Tumbarello M. Isolates with optical density (OD) >0.1 were considered as biofilm-forming. Results. A total of 109 isolates of Candida spp. (C. albicans [n=22], C. parapsilosis [n=22], C. tropicalis [n=22], C.

Prognostic rules for invasive candidiasis risk assessment in ICU patients

nvasive candidiasis is an extremely important problem for severe patients in intensive care units. The high rates of attributive mortality are associated not only with the severity of the patient’s condition, but also with a delayed therapy due to …

Fungal Infections Surveillance in Intensive Care Units

Invasive candidiasis is a common nosocomial infection with high attributable mortality among ICU patients. This study was performed to determine isolation rate of Candida spp. in cardiac surgical ICUs during the period of 2001–2007 and to assess …

Risk Factors for Development of Candidemia in Neonates with Gestational Age Less Than 32 Weeks

The presend study is a retrospective case–control study included 218 infants with gestation age less than 32 weeks hospitalised in the neonatal ICU during 1999–2002. Frequency of the candidemia was 5%. Mortality in newborns with candidemia was 91%. …

Management of Patients with Candidiasis: Overview of New IDSA Guidelines

Сandidiasis remains the most frequently occurred form of invasive fungal infections and represents the major part of superficial mycoses. Important factor that contribute to create an accurate guidelines is the increasing number of candidiasis …

Candidemia In Hospitalized Patients In Saint-Petersburg

During prospective study carried out in 1998–2000 risk factors, spectrum of pathogens, treatment options and mortality in 45 episodes of candidemia in 45 patients from 16 Saint-Petersburg’s hospitals have been analyzed. Majority (84%) of patients …