bacteremia

Objective. To describe results of the first experience of using a syndromic approach to the diagnosis of bacteremia using multiplex panels for real-time polymerase chain reaction (real-time PCR). Materials and Methods. The prospective study included 10 consecutive positive blood cultures obtained from 10 patients in the intensive care unit after cardiac surgery. Hemocultures were carried out in BacT/ ALERT FA Plus vials using a BacT/ALERT 3D 120 incubator (bioMérieux, France).

Objective. To evaluate the results of accelerated identification of microorganisms isolated from positive hemocultures obtained from patients of various departments of a large multi-profile hospital by MALDI-TOF MS and to compare them with classical cultural methods. Materials and Methods. In the period from 2017 to 2018, the study included 109 positive blood cultures from 73 patients from UIA GKB number 40 at the age of 1 to 83 years. Blood samples were taken in aseptic conditions from 2 peripheral veins according to the standard protocol in 12 departments of the health facility.

Objective. To evaluate antimicrobial susceptibility of Enterococcus spp. isolated from blood culture in patients with hematological malignancies. Materials and Methods. Antimicrobial susceptibility of 427 Enterococcus spp. collected from 10 hospitals in 8 cities of Russia in 2002-2016 as part of the multicenter study was tested by the broth microdilution method [CLSI 2015]. Results. Among bloodstream pathogens there was a prevalence of E. faecium (78.2%), followed by E. faecalis (19.7%) and other Enterococcus spp.

Objective. To assess pathogen identification from positive blood cultures by MALDI-TOF mass spectrometry. Materials and Methods. At the first stage, an in vitro study using MALDI-TOF MS and including 11 pathogen species (K. pneumoniae, E. coli, P. aeruginosa, A. baumannii, S. aureus, S. epidermidis, S. haemolyticus, E. faecalis, E. faecium, C. albicans, C. parapsilosis) was performed. This study involved hourly attempts to identify the above listed pathogens by MALDI-TOF MS (Vitek MS, bioMerieux) during incubation until their correct identification.

Daptomycin is the only clinically used member of a cyclic lipopeptides class of antibiotics. Daptomycin has rapid bactericidal activity against not only rapidly growing, but also against slow growing bacterial cells including those in biofilms. …

The study aimed to compare efficacy of microbiologic and molecular genetic methods in identification of an infectious agent in blood samples from HIV-positive patients with septic symptoms. 130 venous blood samples were studied using microbiological …

The review deals with modern methods of indication of infectious agents in the blood. From methodological point of view, they can be divided into two main groups: bacteriologic and molecular. The first group of methods used and improved almost from …

An analysis of all bacteremia cases associated with systemic inflammatory response syndrome among patients hospitalized to City Clinical Hospital named after S.P. Botkin (Moscow) over the 2000–2007 was performed. A total of 303 positive blood culture …

Daptomycin is the first approved member of a cyclic lipopeptides class of antibiotics with anti-Gram(+) activity. In contrast to majority of other antimicrobials daptomycin has rapid bactericidal activity against not only rapidly growing, but also …

Our study showed that chlamydiae were present in the blood from patients with genital and other chlamydial infections. Blood samples tested were positive for C. trachomatis in 92.3% of patients with confirmed chlamydial infection when culture and …