antimicrobial therapy

Compliance of paediatricians to the guidelines on the use of antimicrobials in respiratory infections

Objective. To monitor the level of compliance of paediatricians regarding antimicrobial therapy of acute respiratory infections in children. Materials and Methods. Аnonymous survey of paediatricians of Rostov region was conducted using a questionnaire developed by the authors during 2009-10 and 2014-15. The analysis was performed to assess the compliance with the national recommendations developed by the Union of paediatricians of Russia among the 3 groups of doctors (practicing ≤5 years; 6-20 years; ≥21 years).

Septic Arthritis in Adults

Septic arthritis is a rheumatologic emergency as joint destruction occurs rapidly and can lead to significant morbidity and mortality. The risk of septic arthritis significantly increased in patients with premorbid affected joints (especially with …

Administration of Antimicrobials into Respiratory Tract: Methods to Improve Efficacy in the Treatment of Hospital-Acquired Pneumonia

Despite the availability of substantial theoretical benefits, the method of antibacterial administration via the respiratory tract to treat acute pneumonia has yet to be widely implemented in clinical practice. The introduction of the method is …

Vancomycin Dosing in Hemodialysis Patients

Infectious complications are constitute a serious challenge for patients receiving hemodialysis. With regard to the broad spread of S. aureus isolates with lost susceptibility to β-lactams (MRSA) vancomycin is key option for treatment of these …

Level of Knowledge of Medical Specialists on the Etiology, Diagnosis and Treatment of Infectious Endocarditis in Russia

Objective. To reveal the level of knowledge of medical specialists on the diagnostics and treatment of infective endocarditis (IE). Materials and Methods. Multicenter interviewing of the medical specialists about IE etiology, diagnostics and treatment was conducted during 2012–2013 in 15 cities of different regions of Russia. Results. Overall 530 medical specialists were interviewed. On the question concerning the choice of echocardiographic study only 59,4% of respondents have marked transesophageal route.

Choice of Antimicrobial Agents in Uncomplicated Urinary Tract Infections: How to Make Decision Worthy of Solomon?

Antimicrobials for the treatment of uncomplicated urinary tract infections (UTI) include different drug classes: fluoroquinolones, cephalosporins, beta-lactam/betalactamase inhibitor combinations, aminoglycosides, carbapenems, nitrofurans, …

Current View on Antimicrobial Therapy of Intra-Abdominal Infections

Currently, treatment of intra-abdominal infections is significantly complicated by increased antimicrobial resistance. Inappropriate antimicrobial therapy is one of the reasons for spread of extended spectrum beta-lactamases (ESBL) both in hospital …

Analysis of Antibiotic Usage in Children Living in Orphanages During the 2003–2004 and 2009–2010

Analysis of antibiotic usage in children living in orphanages was performed during two time-periods: 2003–2004 and 2009–2010 with the aim to reveal key problems of antibiotic usage in this population, and to develop measures for improvement. It was …

Short Courses of Antimicrobial Therapy: a New Treatment Paradigm for Community-Acquired Pneumonia?

Over the last years, short treatment courses for different infections, including respiratory tract infections, are increasingly more discussed. This therapeutic approach has some clear benefits: improved compliance, less frequent adverse drug …

Review of Current Guidelines on the Management of Pediatric Patients with Acute Bacterial Rhinosinusitis

Acute bacterial rhinosinusitis (ABRS) is a common disease in pediatric practice, which takes a fifth place among the causes of antimicrobials administration to children. This paper presents a review of current clinical guidelines on the management of …