antimicrobial resistance | CMAC

antimicrobial resistance

Antimicrobial Resistance of H. pylori and Susceptibility Determination Methods

At present, primary, secondary, and multiple resistance of H. pylori to antimicrobial agents tends to increase, which significantly affects efficacy of eradication therapy. There were found significant differences in antimicrobial resistance of H. …

Antimicrobial Resistance of Nosocomial Strains of Escherichia coli in Russian Hospitals

Escherichia coli is one of the main nosocomial pathogens. Recently antibiotic resistance of the pathogen has grown considerably. During our study resistance of 388 nosocomial E. coli isolated in intensive care units (ICUs) different regions of Russia …

Antimicrobial Susceptibility of Causative Agents of Fatal Community-Acquired Pneumonia in Adult Patients

The aim of the study was to determinate the structure of bacterial pathogens and their antimicrobial resistance in adult patients with community-acquired pneumonia (CAP). A total of 57 adult patients from Smolensk and Yartsevo hospitals with severe …

Aminoglycosides: Perspectives for Clinical Use in Russia

The susceptibility to aminoglycoside antimicrobials of Gram-negative nosocomial pathogens in Russia and mechanisms of aminoglycoside resistance has been studied. The production of aminoglycoside-modifying enzymes remains to be the major mechanism of …

Metallo-β-Lactamases: Importance and Detection Methods in Gram-Negative Non-Fermenting Bacteria

More frequently metallo-beta-lactamase (MβL) production becomes a reason of resistance to beta-lactam antibiotics among non-fermentative Gram-negative bacteria, foremost among Pseudomonas spp. and Acinetobacter spp. pathogens. It is evident that …

Antimicrobial Resistance of Clinical Strains of H. influenzae Isolated from Children in Yekaterinburg During 2000–2005

Susceptibility testing of 268 clinical strains of H. influenzaе isolated from children in Yekaterinburg during 2000–2005 was performed by disc diffusion method. Resistance to ampicillin was 13%, to II generation cephalosporins – 3%. There was the …

Current state of Anti-Anaerobic Therapy

Over the last years there is an increase in number of publications that address to the failure of empirical therapy of anaerobic infections which is due to the antimicrobial resistance of pathogens. Hence, it is important to have valid local data on …

Non-Fermenting GramNegative Nosocomial Pathogens in Russian ICUs: Antimicrobial Resistance Problems

In vitro susceptibility study strains of Acinetobacter baumannii and Pseudomonas aeruginosa isolated from patients with nosocomial infections in 31 Russian ICUs was performed (in the framework of «RESORT» survey). The following antibiotics were …

Antimicrobial Resistance of Streptococcus pneumoniae in Russia in 1999–2005: Results of Multicentre Prospective Studies PEHASus-I and PEHASus-II

Objective. Objective: To assess the level, structure and phenotypes of antimicrobial resistance of Streptococcus pneumoniae in different regions of Russia and to evaluate their dynamics in period from 1999 to 2005. Materials and Methods. A total of 1704 S. pneumoniae from 23 cities of Central, North-Western, Southern, Privolgsk, Ural, Siberian and Far-Eastern regions of Russia were included into the study from 1999 to 2005. Susceptibility to 17 antimicrobials was determined by microdilution in accordance with Clinical and Laboratory Standards Institute/National Committee for Clinical Laboratory Standards (CLSI/NCCLS).

Comparative Analysis of Etiology and Antimicrobial Resistance of the Main Nosocomial Pathogens Isolated from the ICUs in Ekaterinburg

Nosocomial infections are very important cause of morbidity and mortality in all developed countries. Results of antimicrobial resistance surveillance performed in the intensive care units of Ekaterinburg (Russia) are presented in the paper. The …