Clinical Microbiology and Antimicrobial Chemotherapy. 2010; 12(1):77-81
A total of 1375 clinical strains of staphylococci isolated from patients in burn units during the 2002–2008 were tested to detect antimicrobial resistance changes during this period. Antimicrobial susceptibility testing was performed by disk-diffusion method on Mueller-Hinton agar. Results of the study showed that staphylococci were a leading cause of nosocomial skin and soft tissue infections in burn patients (35.7%). There were found 2-fold and 2.5-fold increases in prevalence of methicillinresistant Staphylococcus aureus (MRSA) and methicillinresistant coagulase-negative staphylococci, respectively. Also, resistance of staphylococci to aminoglycosides, macrolides, lincosamides, tetracyclines, and fluoroquinolones has risen significantly for the study period. In vitro activity of vancomycin and linesolid against staphylococcal isolates tested was 100%.