antimicrobial activity

Comparative In Vitro Activity of Native Honey and Commercially Available Honey Preparations Against Bacterial Isolates with Extreme Antimicrobial Resistance Phenotypes

This paper presents data on in vitro activity of native honey against bacterial isolates with extreme resistance phenotypes. Comparison of antimicrobial activity of foreign honey preparations approved for the local treatment of infections with that …

oney in the Treatment of Infected Wounds

Honey is a traditional topical treatment for infected wounds was rediscovered in recent years. There are now many published reports describing the effectiveness of honey in rapidly clearing infection from wounds, with no adverse effects. In …

Susceptibility of Streptococcus pyogenes Clinical Strains to Hexetidine and to Systemic Antimicrobals

Minimal inhibitory concentrations (MIC) was used to describe the activity of 8 systemic antimicrobials and antiseptic hexetidine against clinical strains of Streptococcus pyogenes. All tested agents showed high activity against Group A streptococci, …

A New Natural Antiseptic «Galenophyllipt» for the Treatment of Staphylococcal Skin-Muscle Wound Infection in White Mice

Galenophyllipt is a new natural antiseptic for oral administration and topical use that is similar to commercially available medicinal product Chlorophyllipt. The both products are promising agents for clinical use because of their low toxicity and …

Ertapenem – a Newer Carbapenem

The carbapenems are class of beta-lactam antibiotics with exceptionally wide spectrum of activity, beneficial pharmacokinetic parameters and low toxicity as well. Such agents as imipenem and meropenem have already been succesfully used for a long …

Midecamycin: Brief Clinico-pharmacological Review

Macrolides are widely used antibiotics in a variety of infections, especially community-aquired. The clinical success of macrolides is due to their activity against classical causative agents, intracellular pathogens, and some protozoa. Of great …

New oral formulation for the Treatment of Community-Acquired Lower Respiratory Tract Infections

Azithromycin is one of the most commonly used macrolides in the treatment of respiratory tract infections. Azithromycin is a popular antimicrobial due to a number of its unique pharmacokinetic and pharmacodynamic properties. This review describes the …

Amoxicillin/Sulbactam – a New Beta-Lactam/Beta-Lactamase Inhibitor Combination

Beta-lactams are the most commonly used class of antimicrobial agents for the treatment of community-acquired and nosocomial infections. One of the resistance mechanisms for this class is a production of beta-lactamases. To overcome this problem, the …

Azithromycin: Current Clinical Use

Discovery and introduction into the clinical practice of macrolide antibiotics is one of the major advances in the history of antimicrobial therapy. The most prescribed macrolide is azithromycin, which is due to a number of its unique pharmacokinetic …