Clinical Microbiology and Antimicrobial Chemotherapy. 2014; 16(3):212-218
Minimal inhibitory concentrations (MIC) was used to describe the activity of 8 systemic antimicrobials and antiseptic hexetidine against clinical strains of Streptococcus pyogenes. All tested agents showed high activity against Group A streptococci, except tetracycline and chloramphenicol. Time-killing curves showed stable bactericidal effect of hexetidine against strains with both low (4 mg /l) and high (16 mg /l) MICs.