Urinary Tract Infections in Diabetic Patients | CMAC

Urinary Tract Infections in Diabetic Patients

Clinical Microbiology and Antimicrobial Chemotherapy. 2008; 10(3):235-244

​ Haikina E.V., Reshedko G.K., Morozov M.V.
urinary tract infections diabetes mellitus asymptomatic bacteriuria cystitis pyelonephritis antimicrobials
Section
Diseases and Pathogens
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2008; 10(3):235-244

Abstract

Urinary tract infections (UTI) in patients with diabetes mellitus are considered complicated UTI. The specific characteristics of UTI in diabetic patients are the following: high prevalence of asymptomatic bacteriuria, involvement of upper urinary tract, and high risk of recurrence and complications. The main predisposing factors are diabetic nephropathy and autonomous (bladder) neuropathy. The most common pathogens of UTI in diabetics are Gram-negative aerobes, primarily E. coli (75%), followed by other Enterobacteriaceae and nonfermenting bacteria (~15–20% of pyelonephritis cases). Appropriate antimicrobial therapy and good control of the underlying disease are the most important measures in the treatment of UTI in diabetic patients. Antimicrobial therapy should be based on culture results, local data on antimicrobial susceptibility, severity of the disease, and renal function.

  • 1. Хопельман А., Гирлингс С. Инфекции мочевыводящих путей при сахарном диабете. Клин микробиол антимикроб химиотер 2000; 2:40-6.
  • 2. Stapleton A. Urinary tract infections in patients with diabetes. Am J Med 2002; 8:113-30.
  • 3. Довлатян А.А. Лечение острого гнойного пиелонефрита у пациентов с сахарным диабетом. Тер архив 1993; 65:35-9.
  • 4. Лоран О.Б., Пушкарь Д.Ю., Раснер П.И. Ослож­ненные инфекции мочевыводящих путей. Клин антимикроб химиотер 1999; 1:91-4.
  • 5. Patterson J.E., Andriole V.T. Bacterial urinary tract infections in diabetes. Infect Dis Clin North Am 1997; 11:735-50.
  • 6. Joshi N., Caputo G., Weitekamp M., et al. Infections in patients with diabetes mellitus. N Engl J Med 1999; 341:1906-11.
  • 7. Ronald A., Ludwig E. Urinary tract infections in adults with diabetes. Int J Antimicrob Agents 2001; 17:287-92.
  • 8. Nicolle L.E., Friesen D., Harding G.K., Roos L.L. Hospitalization for acute pyelonephritis in Manitoba, Canada during the period from 1989 to 1992:impact of diabetes, pregnancy and aboriginal origin. Clin Infect Dis 1996; 22:1051-6.
  • 9. Cattell W.R. Urinary tract infection and acute renal failure. In:Raine A.E., ed. Advanced renal medicine. Oxford: Oxford University Press, 1992:302-13.
  • 10. Patel N.P., Lavengood R.W., Fernandes M, Ward J.N., Walzak M.P. Gas-forming infections in genitourinary tract. Urology 1992; 39:341-5.
  • 11. Sean T.G., Sheshadri S., Saravu K. Emphy­sematous pyelonephritis. J Assoc Physicians India 2002; 50:1413-5.
  • 12. Williams D.H., Schaeffer A.J. Current concept in urinary tract infections. Minerva Urol Nephrol 2004; 56:15-31.
  • 13. Griffin M.D., Bergstralhn E.J., LarsonT.S. Renal papillary necrosis – a sixteen-year clinical experience. J Am Soc Nephrol 1995; 6:248-56.
  • 14. Синякова Л.А., Антибактериальная терапия острого пиелонефрита. Русский медицинский журнал 2003; 11:1002-6.
  • 15. Carton J.A., Maradona J.A., Nuno F.J., Fernandez-Alvarez R., Perez-Gonzalez F., Asensi V. Diabetes mellitus and bacteraemia:a comparative study between diabetic and non-diabetic patients. Eur J Med 1992; 1:281-7.
  • 16. Mackie A.D., Drury P.L. Urinary tract infection in diabetes mellitus. In:Cattell WR, ed. Infections of the kidney and urinary tract. Oxford:Oxford, Medical Publications (Oxford University Press), 1996, p. 218-33.
  • 17. Naber K.G., Bishop M.C., Bjerklund-Johansen T.E., Botto H., Зek M., Grabe M. Рекомендации Европейской урологической ассоциации по ведению больных с инфекциями почек, мочевыводящих путей и инфекциями мужских половых органов. Современные клинические рекомендации по антимикробной терапии. Под ред. Р.С. Козлова и А.В. Дехнича; Смоленск:МАКМАХ 2007:352-566.
  • 18. Andriole V.T. Asymptomatic bacteriuria in patients with diabetes - enemy or innocent visitor? N Engl J Med 2002; 347:1617-9.
  • 19. Harding G.K., Zhanel G.G., Nicolle L.E., Cheang M.; Manitoba Diabetes Urinary Tract Infection Study Group. Antimicrobial treatment in diabetic women with asymptomatic bacteriuria. N Engl J Med 2002; 347:1576-83.
  • 20. Nicolle LE. Asymptomatic bacteriuria in diabetic women. Diabetes Care 2000; 23:722-30.
  • 21. Geerlings S.E., Stolk R.P., Camps M.J., Net­ten P.M., Hoekstra J.B., Bouter P.K., et al. Risk factors for symptomatic urinary tract infection in women with diabetes. Diabetes Care 2000; 23:1737-41.
  • 22. Ooi S.T., Frazee L.A., Gardner W.G. Management of asymptomatic bacteriuria in patient with diabetes mellitus. Ann Pharmacother 2004; 38:490-3.
  • 23. Шестакова М.В. Инфекции мочевых путей у больных сахарным диабетом. Русский медицинский журнал 1998; 6:788-90.
  • 24. Melekos M.D., Naber K.G. Complicated urinary tract infections. Int J Antimicrob Agents 2000; 15:247-56.
  • 25. Шестакова М.В., Сунцов Ю.И, Дедов И.И. Диабетическая нефропатия:сотояние проблемы в мире и в России. Сахарный диабет 2001; 3:2-4.
  • 26. Hampel C., Gillitzer R., Pahernik S., Melchior S., Thuroff J.W. Diabetes mellitus and bladder function. What should be considered? Urologe A 2003; 42:1556-63.
  • 27. Korzeniowski O.M. Host defense mechanism in the pathogenesis of UTI and UTI in immunocompromised patients. Int J Antimicrob Agents 1994; 4:101-6.
  • 28. Bonadio M., Boldrini E., Forotti G., et al. Asymptomatic bacteriuria in women with diabetes:influence of metabolic control. Clin Infect Dis 2004; 38:41-5.
  • 29. Bonadio M., Meini M., Gigli C., Longo B., Vigna A. Urinary tract infection in diabetic patients. Urol Int 1999; 63:215-19.
  • 30. Goswami R., Bal C.S., Tejaswi S., Punjabi G.V., Kapil A., Kochupillai N. Prevalence of urinary tract infection and renal scars in patients with diabetes mellitus. Diabetes Res Clin Pract 2001; 53:181-6.
  • 31. Chitnavis V., Magnussen C.R. Perinephric abscess due to a coagulase-negative Staphylococcus: case report and review of the literature. J Urol 1993; 149:1530-1.
  • 32. Климко Н.Н. Кандидурия и кандидоз мочевыводящих путей:врачебная тактика. Инфекции и антимикроб терапия 2002; 4:71-6.
  • 33. Sobel J.D. Management of asymptomatic candiduria. Int J Antimicrob Agents 1999; 11:285-8.
  • 34. Nakano H., Oba K., Saito Y., Ouchi M., Yama­shita N., Okamura K. Asymptomatic pyuria in diabetic women. J Nippon Med Sch 2001; 68:405-10.
  • 35. Rollino C., Boero R., Ferro M., Anglesio A., Vaudano G.P., Cametti A. Acute pyelonephritis:analysis of 52 cases. Ren Fail 2002; 24:601-8.
  • 36. Norrby S.R. Urinary tract infections. In: Finch R.G., Greenwood D., Norrby S.R., Whitley R.J., editors. Antibiotics and chemotherapy. Philadelphia: Churchill Livingstone; 2003:764-71.
  • 37. Nicolle L.E., Bradley S., Colgan R., Rice J.C., Schaeffer A., Hooton T.M.; Infectious Diseases Society of America; American Society of Nephrology; American Geriatric Society. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005; 40:643-54.
  • 38. Лоран О.Б., Рафальский В.В. Инфекции мочевыводящих путей. Практическое руководство по антиинфекционной химиотерапии. Под ред. Л.С. Страчунского, Ю.Б. Белоусова, С.Н. Козлова; М. Боргес 2002:243-6.
Views
0 Abstract
0 PDF
0 Crossref citations
Shared