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Personal Experience

Efficacy and Safety of Caspofungin in Children with Invasive Fungal Infections

The prospective study of 19 children (aged of 1 to 17 years) with invasive fungal infections and different forms of immunosupression was conducted. Clinical and microbiological efficacy and safety of caspofungin, as well as analysis of direct costs …

Monitoring of Species Structure and Susceptibility to Antimycotics of Yeast-like Fungi, Isolated from the Genital Tract of Childbearing Age Women

The trends of species structure and susceptibility of yeast-like fungi to antimycotics, isolated from genital tract of women with vulvovaginal candidiasis (n=2828) in 1997–2003 were studied. There was found a tendency to increase in the rate of fungi …

Comparative Analysis of Etiology and Antimicrobial Resistance of the Main Nosocomial Pathogens Isolated from the ICUs in Ekaterinburg

Nosocomial infections are very important cause of morbidity and mortality in all developed countries. Results of antimicrobial resistance surveillance performed in the intensive care units of Ekaterinburg (Russia) are presented in the paper. The …

First Russian Experience of Successful Use of Caspofungin in Invasive Candidiasis in Patient with Severe Hepatic Failure (Clinical case)

A clinical case of the successful use of caspofungin for the treatment of invasive candidiasis, caused by fluconazole- and voriconazole-resistant strain of Candida glabrata, in the patient with severe hepatic failure (Child-Pugh score of 12) due to …

Candida Infections in Very-Low-Birth-Wieight Neonates

The literature devoted to the Candida infections in very-low-birth-weight neonates was reviewed using the Medline and Cochrane databases. Studies in children older than 28 days, full-term newborns, and Candida colonization studies, were excluded from …

Risk Factors for Development of Candidemia in Neonates with Gestational Age Less Than 32 Weeks

The presend study is a retrospective case–control study included 218 infants with gestation age less than 32 weeks hospitalised in the neonatal ICU during 1999–2002. Frequency of the candidemia was 5%. Mortality in newborns with candidemia was 91%. …

Etiological Structure and Antimicrobial Resistance of Pathogens Isolated from Women with Pelvic Inflammatory Diseases

Currently used approaches to antimicrobial prophylaxis (AMP) in abdominal surgery based on the results of multicenter retrospective study of AMP in abdominal surgery in Russian hospitals are analyzed in this paper. Antimicrobial prophylaxis regimens …

First 24-hours Lethtality in Hospitalized Patients with Community-Acquired Pneumonia

Сommunity-acquired pneumonia remains one of the most common infections in population, and despite the wide array of antimicrobials, it is associated with high lethality rate. First 24-hours mortality is an integral characteristic of the quality of …

The Protocols of Antibacterial Therapy

Present article describes the experience of development of the protocols of antimicrobial therapy in one single medical institution – the hospital of Krasnodar municipal medical center. The main purpose for the development of such protocols is the …

Microbiological Diagnosis of Opportunistic Vaginal Infections

Criteria for the evaluation of vaginal biocenosis developed in the Research Center of Obstetrics, Gynecology and Perinatology of the Russian Academy of Medical Sciences (Moscow, Russia) are presented. According to these criteria the microbiological …