Clinical Microbiology and Antimicrobial Chemotherapy. 2005; 7(2):189-196
The literature devoted to the Candida infections in very-low-birth-weight neonates was reviewed using the Medline and Cochrane databases. Studies in children older than 28 days, full-term newborns, and Candida colonization studies, were excluded from the analysis. The most common approaches to the classification of Candida infections in neonates as well as the data on the rates and epidemiology of such infections are reviewed in the article. Risk factors for the main clinical forms of Candida infections are indicated. The analysis of the use of antifungal agents for the treatment and prophylaxis of invasive candidosis was performed.