prophylaxis

Posaconazole is a broad-spectrum triazole antifungal agent with potent activity against various fungi, including yeast and molds, including Mucorales, what makes a key difference with itraconazole and voriconazole. Clinical studies have demonstrated …

Patients undergoing cytotoxic chemotherapy and hematopoietic stem-cell transplantation are at risk for infection. The risk of infections increases with the depth and duration of neutropenia, with the greatest risk occurring in patients who experience …

Travelers’ diarrhea is the most common infectious disease in this subpopulation and usually develops within the first week of travel. This review presents summarized data on epidemiology and etiology of travelers’ diarrhea. Nonspecific precautions …

Prophylaxis of nosocomial legionellosis is a currently adopted component of the general strategy to fight hospital-acquired infections. In the early 1980s, nosocomial outbreaks of legionnaire disease associated with the high mortality (20 to 40%) …

Central venous access is commonly used in clinical practice for a wide spectrum of procedures, such as hemodialysis, long-term chemotherapy, parenteral nutrition, etc. The main complications limiting the duration of use of central catheters and …

Invasive mycoses in patients with severe diseases – ICU patients, patients with hematological malignancies and after solid organ transplantations represent a significant target for the use of prophylactic, empirical and pre-emptive antifungal …

For the first time in Russian economic conditions and with use of mathematic modeling, clinical-economic study of posaconazole in comparison with fluconazole/itraconazole for primary prophylaxis of invasive mycoses in patients with severe neutropenia …

Over the last years there was a significant improvement in diagnostics and prophylaxis of legionellosis that is due to introduction of current standards of laboratory diagnosis and quantitative analysis of the pathogen in the environmental objects. …

In spite of the fact that legionellosis is known as a human infectious disease for more than 25 years there is still quite a few difficulties and open problems. At the present article the following topics are described in detail: taxonomy, general …

Pneumonia is the common bacterial infection among elderly patients in nursing homes and long-term care facilities. Pneumonia in that population is often severe and associated with high mortality. The high prevalence of this infection, diagnostic …