Diseases and Pathogens

Objective. To study prospectively clinical course of hospital-acquired pneumonia (HAP), mortality, and risk factors for poor outcome as well as etiology and antibiotic resistance of HAP in trauma patients; to assess antimicrobial therapy in patients with head trauma and orthopedic trauma in Smolensk Clinical Hospital of Emergency Medical Care. Materials and Methods. A prospective observational study in 96 patients with head trauma or orthopedic trauma and concurrent HAP, confirmed by clinical examination, chest X-ray, and Clinical Pulmonary Infection Scale (CPIS) score of ≥5.

In vitro activity of 13 antimicrobials (amikacin, cefepime, cefoperazone, cefoperazone/sulbactam, cefotaxime, ceftazidime, ciprofloxacin, gentamicin, imipenem, levofloxacin, meropenem, piperacillin, piperacillin/tazobactam) against 464 Acinetobacter …

Central venous access is commonly used in clinical practice for a wide spectrum of procedures, such as hemodialysis, long-term chemotherapy, parenteral nutrition, etc. The main complications limiting the duration of use of central catheters and …

Acute uncomplicated cystitis is one of the most prevalent community-acquired infections in urological practice. One of the crucial moments in the therapy of urinary tract infections is the administration of antibacterial drugs. The following groups …

This review contains brief information on the epidemiology of salmonellosis as well as the modern classification and nomenclature of Salmonella genus. The main mechanisms of antimicrobial resistance in Salmonella and their prevalence are summarized. …

Invasive mycoses in patients with severe diseases – ICU patients, patients with hematological malignancies and after solid organ transplantations represent a significant target for the use of prophylactic, empirical and pre-emptive antifungal …

Efficacy of antimicrobial treatment regimens in pregnant or non-pregnant women with bacterial vaginosis (BV) is difficult to evaluate. It’s due to variability of the diagnosis and cure criteria currently used in clinical studies. This paper …

Respiratory tract infections are the most common human infectious diseases. These infections may cause serious complications and cause tremendous economic losses. Therefore the adequate treatment of different types of respiratory infections, …

Among adolescent children urinary tract infections (UTI) occurs in around 1% of male and up to 3% of female persons. In adolescent girls during the last decades the frequency of sexually transmitted infections (STI) is rising. Non-treated infections …

Invasive candidiasis is a common nosocomial infection with high attributable mortality among ICU patients. This study was performed to determine isolation rate of Candida spp. in cardiac surgical ICUs during the period of 2001–2007 and to assess …