Diseases and Pathogens

Pseudomonas aeruginosa is one of the most important pathogens causing opportunistic infections. This literature review contains analysis of articles on molecular characteristics of P. aeruginosa virulence factors, as well as the pathogenesis of …

The article presents the current classification of herpesviruses, clinical features of infections caused by β-herpesviruses, as well as methods of laboratory diagnosis and treatment of these infections.

Objective. To investigate etiology of infective endocarditis in Russian Federation. Materials and Methods. Multicenter prospective (September 2011 to December 2013) and retrospective (January 2006 – September 2011) studies to investigate etiology of infective endocarditis (IE) were performed at medical institutions in 10 Russian cities. Patients with definite or possible diagnosis of IE who have at least 1 blood culture collected were enrolled in the study. Results. A total of 401 patients with IE were included in the analysis: 161 (40.

The study aimed to compare efficacy of microbiologic and molecular genetic methods in identification of an infectious agent in blood samples from HIV-positive patients with septic symptoms. 130 venous blood samples were studied using microbiological …

This paper presents a comparative analysis of distribution of hepatitis A, B, C and E as well as opportunistic infections among immunosuppressed patients and healthy people. Results of this epidemiological study suggest hepatitis E as an …

Despite the availability of substantial theoretical benefits, the method of antibacterial administration via the respiratory tract to treat acute pneumonia has yet to be widely implemented in clinical practice. The introduction of the method is …

Chronic airway inflammation and infection are the main cause of mortality in patients with cystic fibrosis (CF), therefore effective antimicrobial therapy is important part of treatment of CF-lung disease. In the article, an overview on present …

Objective. To reveal the level of knowledge of medical specialists on the diagnostics and treatment of infective endocarditis (IE). Materials and Methods. Multicenter interviewing of the medical specialists about IE etiology, diagnostics and treatment was conducted during 2012–2013 in 15 cities of different regions of Russia. Results. Overall 530 medical specialists were interviewed. On the question concerning the choice of echocardiographic study only 59,4% of respondents have marked transesophageal route.

Antimicrobials for the treatment of uncomplicated urinary tract infections (UTI) include different drug classes: fluoroquinolones, cephalosporins, beta-lactam/betalactamase inhibitor combinations, aminoglycosides, carbapenems, nitrofurans, …

Siphoviridae family bacteriophages are known to play a major role in horizontal transfer of virulence genes among Staphylococcus aureus. Integrase group 3 phages transfer genes encoding staphylokinase (sak), staphylococcal complement inhibitor (scn), …