Аннотация
В мае 2016 г. FDA одобрило внесение изменений в инструкцию по применению системных препаратов фторхинолонов и рекомендовало ограничить их назначение для лечения острого синусита, неосложнённых инфекций мочевыводящих путей и обострения хронического бронхита. Это решение было основано на рекомендации консультативных комиссий FDA, которые пришли к заключению, что риск развития редких серьёзных и потенциально перманентных побочных эффектов со стороны костно-мышечной, центральной и периферической нервной систем, которые могут одновременно развиваться у одного и того же пациента, перевешивает потенциальную пользу фторхинолонов при этих инфекциях. В данной статье анализируются данные об эффективности фторхинолонов и других антибиотиков при остром синусите, обострении хронического бронхита и неосложнённых инфекциях мочевыводящих путей, представленные на заседании консультативных комиссий FDA и опубликованные в доступной научной литературе.
ФГАОУ ВО «Российский университет дружбы народов» Минобрнауки России, Москва, Россия
ФГАОУ ВО «Российский университет дружбы народов» Минобрнауки России, Москва, Россия
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