Левофлоксацин в лечении внебольничной пневмонии: 20 лет успешного применения | КМАХ

Левофлоксацин в лечении внебольничной пневмонии: 20 лет успешного применения

Клиническая Микробиология и Антимикробная Химиотерапия. 2013; 15(1):35-46

​ Синопальников А.И., Романовских А.Г.
левофлоксацин спектр активности фармакокинетика безопасность эффективность внебольничная пневмония
Раздел
Антимикробные препараты
Тип
Журнальная статья
Публикация
Клиническая Микробиология и Антимикробная Химиотерапия. 2013; 15(1):35-46

Аннотация

Согласно результатам международных пост­регистрационных исследований, левофлоксацин относится к числу наиболее востребованных антимикробных препаратов. Одним из основных показаний для назначения этого антибиотика является внебольничная пневмония. В настоящем обзоре, посвящённом 20­летию появления левофлоксацина на фармацевтическом рынке, представлены данные, характеризующие его терапевтическую эффективность при данном заболевании, обсуждаются фармакодинамические и фармакокинетические особенности, а также вопросы безопасности его применения. Несмотря на многолетнюю историю широкого использования, левофлоксацин остаётся одним из наиболее успешных антибиотиков, применяемых для лечения больных внебольничной пневмонией, что находит отражение в современных международных рекомендациях, также представленных в предлагаемом обзоре.

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