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probiotics

Sepsis caused by Lactobacillus: a clinical case report

The article describes a clinical observation of a 3 months old patient with ALK-positive histiocytosis complicated by sepsis caused by Lactobacillus paracasei. A pure culture of the microorganism was obtained by seeding on blood agar, and its …

Whole-genome analysis of a probiotic strain Lactocaseibacillus – identification of genetic determinants for bacteriocin production as a basis for standardization of mono- and multicomponent probiotics

Objective. Conducting a whole-genome study and bioinformatic analysis of a Lacticaseibacillus strain to confirm taxonomic affiliation, identify genetic determinants of metabolic activity, stress resistance, and bacteriocin production as a criterion for the standardization of mono- and multi-component probiotics. Materials and Methods. The object of the study was a strain isolated from a coloproctology patient in 2024. Cultivation was carried out on MRS medium under microaerophilic conditions. Wholegenome sequencing was performed on the Oxford Nanopore Technologies MinION platform (R10.

Probiotics as a means of strengthening commensal skin microbiota in the treatment of infected soft tissue wounds

Probiotics can promote wound healing by stimulating the production of immune cells, activation of reparative regeneration processes as well as show antagonism against pathogenic microflora. The data presented in this review of the literature indicate …

Mechanisms of microbial interactions between probiotic microorganisms and Helicobacter pylori

This review summarizes the most recent data about the mechanisms of microbial interactions between probiotic microorganisms and H. pylori. The review examines the influence of H. pylori on the gastrointestinal microbiota, interspecific interactions …

Combination of gastroprotectors and probiotics in the eradication of H. pylori infection: results of a randomized comparative clinical trial

Objective. To compare efficacy and safety of 14-day triple eradication therapy with the addition of methylmethionine sulfonium chloride and a probiotic complex and 14-day triple eradication therapy boosted with bismuth tripotassium dicitrate and a probiotic complex in a prospective comparative randomized clinical trial. Materials and Methods. A total of 70 patients with confirmed H. pylori infection were enrolled into the study. The first group (n = 35) received esomeprazole 20 mg 2 bid, clarithromycin 500 mg bid and amoxicillin 1000 mg bid for 14 days, methylmethionine sulfonium chloride 300 mg once a day for 1 month, probiotic complex (bifidobacteria [Bifidobacterium longum CBT BG7, Bifidobacterium lactis CBT BL3, Bifidobacterium bifidum CBT BF3], lactobacilli [Lactobacillus acidophilus CBT LA1, Lactobacillus rhamnosus CBT LR5], Streptococcus thermophilus CBT ST3) 1 capsule once a day for 1 month.

Psychobiotics: a new way in psychopharmacology, or How do bacteria manage our brain?

Psychobiotics are a special class of probiotics that have a beneficial effect on human mental health. During the last decade, convincing evidence has emerged that the gut microbiome influences mental health, cognitive abilities (learning and memory), …

Gastrointestinal adverse drug reactions and antibiotic-associated diarrhea during antibiotic therapy in outpatient practice: prevention and treatment

Adverse drug reactions affecting gastrointestinal tract, quite often with the development of antibioticassociated diarrhea, are the most common undesirable effects of antibiotic therapy in outpatient practice. This review provides modern approaches …

The evidence base and practical approaches to probiotic use in clinical practice: a focus on Lactobacillus rhamnosus GG and Bifidobacterium lactis Вb-12

Over the last 20 years, there is an ever-increasing interest in the use of probiotics for the variety of health problems worldwide. However, the evidence base for various probiotic microorganisms differs significantly. This review provides data on …

New probiotic strain Streptococcus salivarius K12 in clinical practice

Over the last decades, probiotic strains for topical administration (including oral cavity) have appeared in clinical practice. Streptococcus salivarius K12 is a promising probiotic for prevention and treatment of the upper respiratory tract and ENT …

Current approaches to prophylaxis and treatment of travelers’ diarrhea

Travelers’ diarrhea is the most common infectious disease in this subpopulation and usually develops within the first week of travel. This review presents summarized data on epidemiology and etiology of travelers’ diarrhea. Nonspecific precautions …