Probiotics as a means of strengthening commensal skin microbiota in the treatment of infected soft tissue wounds

Clinical Microbiology and Antimicrobial Chemotherapy. 2023; 25(3):239-246

​ Tulupov A.A., Beschastnov V.V., Tyumenkov Yu.O., Kovalishena O.V., Shirokova I.Yu., Belova I.V., Tochilina A.G., Solovieva I.V.
10.36488/cmac.2023.3.239-246
probiotics skin microbiota soft tissue wounds wound infection treatment
Section
Diseases and Pathogens
Type
Review
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2023; 25(3):239-246

Abstract

Probiotics can promote wound healing by stimulating the production of immune cells, activation of reparative regeneration processes as well as show antagonism against pathogenic microflora. The data presented in this review of the literature indicate that the local use of probiotics to enhance the microbiota of the skin in the fight against pathogens of wound infection is a scientifically sound direction demonstrating clinically significant positive results. The results of laboratory and experimental studies can form the basis for further development and development of methods for the clinical use of probiotics in the treatment of patients with infected wounds.

Alexander A. Tulupov

Privolzhsky Research Medical University, Nizhny Novgorod, Russia

Beschastnov V.V.

Privolzhsky Research Medical University, Nizhny Novgorod, Russia

Tyumenkov Yu.O.

Privolzhsky Research Medical University, Nizhny Novgorod, Russia

Kovalishena O.V.

Privolzhsky Research Medical University, Nizhny Novgorod, Russia

Shirokova I.Yu.

Privolzhsky Research Medical University, Nizhny Novgorod, Russia

Belova I.V.

Privolzhsky Research Medical University, Nizhny Novgorod, Russia
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russia

Tochilina A.G.

Privolzhsky Research Medical University, Nizhny Novgorod, Russia
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russia

Solovieva I.V.

Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russia

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