antimicrobial therapy

Practice Guidelines for the Antimicrobial Therapy in Neutropenic Patients with Cancer (According to the Guidelines of Infections Diseases Society of America)

Clinical Microbiology and Antimicrobial Chemotherapy. 2003; 5(1):47-73
Febrile neutropenia is becoming significant problem in Russian medical institutions. Changes in spectrum of causative pathogens, increase of the number of neutropenic patients and emergence of antimicrobial resistance – all the above factors require …

Guidelines on Antibacterial Therapy of Urinary Tract Infections in Children

Clinical Microbiology and Antimicrobial Chemotherapy. 2002; 4(4):337-346
In the present guidelines the tactics of the choice of antibiotics in community-acquired urinary tract infections in children are presented. The guidelines are based on the results of multicentre study of antimicrobial resistance of the most common …

Acute Bacterial Rhinosinusitis: Current Approaches to the Diagnostic and Antibacterial Therapy in Outpatient Settings

Clinical Microbiology and Antimicrobial Chemotherapy. 2002; 4(1):70-82
Acute rhinosinusitis is one of the most common disorders in otolaryngology and is on 5th place among all diseases based on the amount of all prescribed antimicrobials. But a number of problems in the antimicrobial therapy of this pathology still …

Antibiotic-Associated Diarrhea

Clinical Microbiology and Antimicrobial Chemotherapy. 2002; 4(1):22-32
Diarrhea, which is associated with the usage of antimicrobials, is one of the important problems in clinical practice. This article reviews the questions of etiology, pathogenesis and epidemiology of antibiotic-associated diarrhea (AAD). Clinical …

Efficacy of Cefepime Monotherapy and The Combination of Ceftazidime with an Aminoglycoside in The Treatment of Infections in Oncology Patients with Severe Neutropenia

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(4):339-347
The combination of ceftazidime with an aminoglycoside is a commonly used standard for empiric therapy of febrile neutropenia. A lot of attention is paid to the development of effective monotherapy for the treatment of this condition. One of the most …

Role of Fusidic Acid in Clinical Practice

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(4):324-338
The widespread of multy-resistant Gram-positive pathogens, especially methicillin-resistant staphylococci made us to reconsider our attitude to such an «old» drug as fusidic acid and to draw attention to its usefulness in therapy of the …

Ventilator-Associated Pneumonia: Debatable Questions in Terminology, Diagnostics and Empirical Antimicrobial Therapy

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(3):198-208
The present literature review is devoted to the one of the actual problems in the intensive care units – to the nosocomial pneumonia that is developing during mechanical ventilation (ventilator-associated pneumonia – VAP) in patients with different …

Therapy of Exacerbation of Chronic Bronchitis in Ambulatory Practice: the Results of the Pharmacoepidemiological Study

Clinical Microbiology and Antimicrobial Chemotherapy. 2001; 3(2):148-155
Case histories of outpatients with acute exacerbation of chronic bronchitis (AECB) were analyzed. Diagnoses were classified according to the ICD-10, antimicrobials – to the ATC classification. Altogether 783 case histories of patients aged from 16 to …

Antimicrobials Prescription Pattern in Outpatient Adults with Community-Acquired Pneumonia

Clinical Microbiology and Antimicrobial Chemotherapy. 2000; 2(3):74-81
Case histories of outpatients with community-acquired pneumonia (CAP) who had not required hospitalization were randomly selected in seven regions of Russia for retrospective analysis. Diagnoses were classified according to the ICD-10; antimicrobials …

Polymyxins – New Approaches to the Old Antimicrobials

Clinical Microbiology and Antimicrobial Chemotherapy. 2000; 2(3):68-73
Spread of multiresistant bacteria makes us to reconsider our attitude to some well-known old antimicrobials, including polymyxins – a class of polypeptide antibiotics that are active against many multiresistant gram-negative nosocomial pathogens – …