antimicrobial resistance | CMAC

antimicrobial resistance

Daptomycin – the Review of Pharmacological, Clinical and Microbiological Characteristics

Daptomycin is the first approved member of a cyclic lipopeptides class of antibiotics with anti-Gram(+) activity. In contrast to majority of other antimicrobials daptomycin has rapid bactericidal activity against not only rapidly growing, but also …

Resistance Trends and Epidemiology of Acinetobacter Infections in Russia

In vitro activity of 13 antimicrobials (amikacin, cefepime, cefoperazone, cefoperazone/sulbactam, cefotaxime, ceftazidime, ciprofloxacin, gentamicin, imipenem, levofloxacin, meropenem, piperacillin, piperacillin/tazobactam) against 464 Acinetobacter …

Antimicrobial Resistance of Nosocomial Staphylococci Isolated from Burn Center Patients in 2002–2008

A total of 1375 clinical strains of staphylococci isolated from patients in burn units during the 2002–2008 were tested to detect antimicrobial resistance changes during this period. Antimicrobial susceptibility testing was performed by …

Antimicrobial Resistance of H. pylori and Susceptibility Determination Methods

At present, primary, secondary, and multiple resistance of H. pylori to antimicrobial agents tends to increase, which significantly affects efficacy of eradication therapy. There were found significant differences in antimicrobial resistance of H. …

Antimicrobial Resistance of Nosocomial Strains of Escherichia coli in Russian Hospitals

Escherichia coli is one of the main nosocomial pathogens. Recently antibiotic resistance of the pathogen has grown considerably. During our study resistance of 388 nosocomial E. coli isolated in intensive care units (ICUs) different regions of Russia …

Antimicrobial Susceptibility of Causative Agents of Fatal Community-Acquired Pneumonia in Adult Patients

The aim of the study was to determinate the structure of bacterial pathogens and their antimicrobial resistance in adult patients with community-acquired pneumonia (CAP). A total of 57 adult patients from Smolensk and Yartsevo hospitals with severe …

Aminoglycosides: Perspectives for Clinical Use in Russia

The susceptibility to aminoglycoside antimicrobials of Gram-negative nosocomial pathogens in Russia and mechanisms of aminoglycoside resistance has been studied. The production of aminoglycoside-modifying enzymes remains to be the major mechanism of …

Metallo-β-Lactamases: Importance and Detection Methods in Gram-Negative Non-Fermenting Bacteria

More frequently metallo-beta-lactamase (MβL) production becomes a reason of resistance to beta-lactam antibiotics among non-fermentative Gram-negative bacteria, foremost among Pseudomonas spp. and Acinetobacter spp. pathogens. It is evident that …

Antimicrobial Resistance of Clinical Strains of H. influenzae Isolated from Children in Yekaterinburg During 2000–2005

Susceptibility testing of 268 clinical strains of H. influenzaе isolated from children in Yekaterinburg during 2000–2005 was performed by disc diffusion method. Resistance to ampicillin was 13%, to II generation cephalosporins – 3%. There was the …

Current state of Anti-Anaerobic Therapy

Over the last years there is an increase in number of publications that address to the failure of empirical therapy of anaerobic infections which is due to the antimicrobial resistance of pathogens. Hence, it is important to have valid local data on …