Phenotypic and Genetic Characteristics of Pathogens Causing Burn Wound Infections

Clinical Microbiology and Antimicrobial Chemotherapy. 2012; 14(4):342-346

Type
Journal article

Abstract

The analysis of the results of infectious agents present on a wound was performed and the leading role of staphylococcus was revealed in the burn centre of Nizhny Novgorod Research Institute of Traumatology and Orthopaedics during the period of 2008–2011. The quantity of staphylococcus among the other agents of wound burn infection reached 44%. The role of coagulase-negative staphylococci has increased, which was 53,8% of all Staphylococcus spp. isolated in 2011 and a half of them are carriers of mecA gene. Non-fermenting Gram-negative rods take a second place in the structure of pathogens, 39% of them being P. aeruginosa and 50,8% – Acinetobacter spp. during the observation period. Resistance phenotypes in staphylococci and non-fermenting Gram-negative rods indicate their high resistance to antimicrobial agents. Expression of metallo-beta-lactamase VIM-2 type is revealed in 40,8% of Pseudomonas, all these strains belonged to one clonal line ST235.

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