antimicrobial resistance | CMAC

antimicrobial resistance

Antimicrobial Resistance of the Respiratory Strains of Streptococcus pyogenes in Russia During 1999–2009

Objective. Objectives. To evaluate the level, structure and phenotypes of antimicrobial resistance in clinical respiratory strains of Streptococcus pyogenes in different regions of Russia during 1999–2009. Materials and Methods. In total 804 respiratory strains of S. pyogenes from different regions of Russia were included in the study. Susceptibility to 18 antimicrobials was evaluated by the standard broth microdilution method according to EUCAST 2012 recommendations. Results. β-Lactams remaine highly active against all tested strains.

A New Method for Evaluation of Antimicrobial Resistance of Bacteria in Biofilms

At the present article we evaluate a relatively new method of the evaluation of activity of antimicrobials against bacterial biofilms. This method combines the possibilities of simultaneous evaluation of bacterial survival in biofilm in the presence …

Independent Acquisition of Quinolone Resistance in Clonally Related Nosocomial Strains of Salmonella Typhimurium Due to Hypermutability

Here we report on a high incidence of quinolone resistance (43,1%) among nosocomial CTX-M-5 ESBLproducing S. Typhimurium isolates belonging to a single clonal group isolated in Russia, Belarus, and Kazakhstan. The resistance mechanism in all cases …

Antimicrobial Resistance of Bacteria in Biofilms

Different mechanisms of antimicrobial resistance development in biofilm bacteria are reviewed in the article. Practical approaches to the susceptibility testing of bacteria in biofilms are analyzed.

Clonal dissemination of CTX-M-5-producing nosocomial strains of Salmonella Typhimurium in Russia, Belarus, and Kazakhstan

In this paper, the evidence of broad geographic dissemination of Salmonella enterica serovar Typhimurium strains belonging to a single genetic lineage is presented. The isolates described possess resistance to oxiiminocephalosporines due to …

Antimicrobial Stewardship as a Renascence of the ‘Golden Age’ of Antibiotics

Infections caused by resistant microorganisms are of particular concern for both healthcare providers and public health authorities due to associated significant social and economic losses. Improper use of antimicrobial agents, selective pressure, …

Escherichia coli as a Nosocomial Pathogen in ICUs

Over the last years, Gram-negative bacilli are the leading cause of nosocomial infections in different part of the world. Intensive care units (ICUs) differ from other units by continuous healthcare worker-to-patient contacts, large number of …

Phenotypic and Genotypic Characteristics of Pneumococci Isolated from Patients with Pneumococcal Meningitis

Antimicrobial susceptibility, serotype distribution, and multilocus sequence types of Streptococcus pneumoniae isolated from the patients with meningitis were determined. We tested a total of 84 isolates which have been obtained in Moscow during …

Antimicrobial Resistance of Gram-negative Bacteria Isolated from Biopsy Samples in Patients with Ulcerative Colitis

Objective. To investigate spectrum and antimicrobial susceptibility of colonic microorganisms isolated from biopsy samples in patients with ulcerative colitis. Materials and Methods. A total of 34 patients with ulcerative colitis (19 to 75 years of age) treated in proctology unit (Surgery Clinic of Samara State Medical University) during the 2009–2010 were examined in this study. Results. A total of 70 gram-negative isolates were obtained, of which Enterobacteriaceae were the most predominant pathogens.

Antimicrobial Resistance of Streptococcus pneumoniae in Russia over the 1999–2009: Results of Multicenter Prospective Study PEHASus

Objective. To assess antimicrobial resistance and its trends among Streptococcus pneumoniae in different regions of Russia over the 1999-2009. Materials and Methods. A total of 2419 S. pneumoniae strains from different cities of Central, NorthWestern, Southern, Volga, Ural, Siberia, Far-Eastern regions of Russia were included into the study over the period from 1999 to 2009. Susceptibility to 23 antimicrobials was determined using microdilution method according to Clinical and Laboratory Standards Institute (CLSI) guidelines.