antimicrobial resistance

Objective. Aim. To evaluate the antimicrobial susceptibility of group A streptococci (GAS) of different emm-genotypes, isolated from patients with invasive and non-invasive skin and soft tissue infections. Materials and Methods. Overall 91 strains of GAS isolated during 2008–2011 from patients with invasive and non-invasive skin and soft tissue infections hospitalized in one Moscow’s hospital were included in the study. Identification was done by latex agglutination, genotyping — by CDC protocol.

One of the main mechanisms of resistance of Gramnegative microorganisms to antibiotics is enzymatic hydrolysis by beta-lactamases (for example, metallobeta-lactamases). Searching of paths of strengthening of carbapenems action is possible due to …

Objective. To investigate etiology of infective endocarditis in Russian Federation. Materials and Methods. Multicenter prospective (September 2011 to December 2013) and retrospective (January 2006 – September 2011) studies to investigate etiology of infective endocarditis (IE) were performed at medical institutions in 10 Russian cities. Patients with definite or possible diagnosis of IE who have at least 1 blood culture collected were enrolled in the study. Results. A total of 401 patients with IE were included in the analysis: 161 (40.

In total 284 clinical nosocomial S. aureus strains isolated in 2011–2012 from patients hospitalized in 25 hospitals in 18 Russian cities were included in the study. Susceptibility to 19 antimicrobials was assessed by serial dilution method in …

Pseudomonas aeruginosa is the most abundant bacterial species causing nosocomial infections in Russia. In this paper, we report the data on antimicrobial susceptibility of 343 isolates of P. aeruginosa collected in 25 hospitals of 18 cities of Russia …

Acinetobacter baumannii and related species of the Acinetobacter calcoaceticus-baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 252 …

Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 573 isolates of Enterobacteriaceae collected in 25 hospitals of 18 cities of …

Streptococcus pneumoniae strains isolated from children of Krasnoyarsk (Siberia, Russian Federation) were examined. Authors determined Streptococcus pneumoniae serotypes and antimicrobial resistance. 16.7% of strains were multiple resistant with high …

Objective. To study antimicrobial resistance of Haemophilus influenzae and its trends in different Russian regions over the period of 2004–2009. Materials and Methods. This study included consecutive clinical strains of H. influenzae obtained from patients with different infections (pneumonia, acute otitis media, meningitis, bacteremia, COPD exacerbation, etc.) in Central, Volga, Ural, and Siberian federal districts of Russia over the period of 2004–2009. Susceptibility to 12 antimicrobial agents was determined by broth microdilution method according to the Clinical Laboratory Standards Institute guidelines (CLSI 2013).

Infections caused by drug resistant pathogens are ever-increasing problem in hospital and outpatient settings. Nosocomial infections are associated with treatment failures, prolonged length of hospital stay and increased mortality. Chlorhexidine …